Quantitative CARS Microscopic Detection of Analytes and Their Isotopomers in a Two-Channel Microfluidic Chip

被引:36
作者
Bergner, Gero [1 ,3 ]
Chatzipapadopoulos, Susana [3 ]
Akimov, Denis [3 ]
Dietzek, Benjamin [3 ,4 ]
Malsch, Daniell [3 ]
Henkel, Thomas [3 ]
Schluecker, Sebastian [1 ,2 ]
Popp, Juergen [3 ,4 ]
机构
[1] Univ Wurzburg, Inst Phys Chem, D-97074 Wurzburg, Germany
[2] Univ Osnabruck, Dept Phys, D-49069 Osnabruck, Germany
[3] Inst Photon Technol, D-07745 Jena, Germany
[4] Univ Jena, Inst Phys Chem, D-07743 Jena, Germany
关键词
analytical methods; CARS microscopy; isotopomers microfluidics; Raman spectroscopy; RAMAN; MICROSPECTROSCOPY;
D O I
10.1002/smll.200900807
中图分类号
O6 [化学];
学科分类号
0703 ;
摘要
Fast and quantitative detection of organic analytes is achieved by coherent anti-Stokes Raman scattering (CARS) microscopy using a two-channel microfluidic chip in combination with deuterated isotopomers as a reference (see picture). This experimental design enables the simultaneous measurement of both the chemically relevant Raman-resonant signal and the non-Raman-resonant background.
引用
收藏
页码:2816 / 2818
页数:3
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