Recent advances of ratiometric electrochemiluminescence biosensors

被引:72
作者
Huo, Xiao-Lei [1 ,2 ]
Lu, Hai-Jie [1 ,2 ]
Xu, Jing-Juan [1 ,2 ]
Zhou, Hong [3 ]
Chen, Hong-Yuan [1 ,2 ]
机构
[1] Nanjing Univ, State Key Lab Analyt Chem Life Sci, Sch Chem & Chem Engn, Nanjing 210023, Jiangsu, Peoples R China
[2] Nanjing Univ, Collaborat Innovat Ctr Chem Life Sci, Sch Chem & Chem Engn, Nanjing 210023, Jiangsu, Peoples R China
[3] Qingdao Univ Sci & Technol, Coll Chem & Mol Engn, Minist Educ, Key Lab Opt Elect Sensing & Analyt Chem Life Sci, Qingdao 266042, Shandong, Peoples R China
基金
中国国家自然科学基金; 国家重点研发计划;
关键词
RESONANCE ENERGY-TRANSFER; IN-SITU GENERATION; SENSITIVE DETECTION; BIPOLAR ELECTRODE; QUANTUM DOTS; COLOR-SWITCH; APTASENSOR; SIGNAL; AMPLIFICATION; FLUORESCENCE;
D O I
10.1039/c9tb01823a
中图分类号
TB3 [工程材料学]; R318.08 [生物材料学];
学科分类号
0805 ; 080501 ; 080502 ;
摘要
Ratiometric electrochemiluminescence (ECL) assays have been widely applied in biosensing because of eliminated outside interferences and improved reliability in detection. In order to construct ratiometric ECL biosensors with high sensitivity and reliability, it is critical to find two signal emitters with suitable applied potentials or emission wavelengths. This review aims to discuss recent advances and trends of ratiometric ECL biosensors in terms of ECL materials and corresponding ratiometric sensing approaches. We focus on four types of ratiometric ECL biosensors based on particular ECL materials and ratiometric sensing strategies.
引用
收藏
页码:6469 / 6475
页数:7
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