Endoscopic Ultrasound-guided Celiac Plexus Neurolysis to Alleviate Intractable Pain Caused by Advanced Pancreatic Cancer

被引：9

作者：

Lou, Songmei ^{[1
]}

机构：

[1] Zhejiang Univ, Sch Med, Sir Run Run Shaw Hosp, Dept Gen Surg, 3 Qingchun Rd, Hangzhou 310000, Zhejiang, Peoples R China

来源：

SURGICAL LAPAROSCOPY ENDOSCOPY & PERCUTANEOUS TECHNIQUES | 2019年 / 29卷 / 06期

关键词：

pancreatic cancer; celiac plexus neurolysis; pain; endoscopic ultrasound;

D O I：

10.1097/SLE.0000000000000683

中图分类号：

R61 [外科手术学];

学科分类号：

摘要：

This study aimed to analyze the clinical safety and effectiveness of endoscopic ultrasound-guided celiac plexus neurolysis (EUS-CPN) in alleviating intractable abdominal pain caused by advanced pancreatic cancer. A total of 58 patients with inoperable pancreatic cancer who underwent EUS-CPN from May 2015 to December 2017 were enrolled. Pain levels before and after EUS-CPN were assessed and compared using the Visual Analogue Scale. The preoperative Visual Analogue Scale score was 8.2 +/- 2.3, which decreased significantly to 3.6 +/- 1.5 at 2 days after EUS-CPN and to 2.2 +/- 0.8 after 1 month. The response rate was 79.3%. No patient experienced serious complications; 14 patients experienced mild, transient side effects (self-limiting diarrhea, reflex hypotension, and worsening of abdominal pain) that resolved within 48 hours. For pancreatic cancer patients, EUS-CPN can effectively control pain with minimal adverse effects.

引用

页码：472 / 475

页数：4

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