Synthesis of triclinic calcium pyrophosphate crystals

被引：9
作者：
Groves, P. J.
Wilson, R. M.
Dieppe, P. A.
Shellis, R. P.
机构：
[1] Univ Bristol, Sch Dent, Div Restorat Dent, Bristol BS1 2LY, Avon, England
[2] Univ London Queen Mary Coll, London E1 4NS, England
[3] Univ Bristol, MRC Hlth Serv Res Collaborat, Dept Social Med, Bristol, Avon, England
来源：
JOURNAL OF MATERIALS SCIENCE-MATERIALS IN MEDICINE | 2007年 / 18卷 / 07期
基金：
英国医学研究理事会;
关键词：
AQUEOUS-SOLUTIONS; DIHYDRATE;
D O I：
10.1007/s10856-007-0129-y
中图分类号：
R318 [生物医学工程];
学科分类号：
0831 ;
摘要：
This paper presents a method for preparing crystals of triclinic calcium pyrophosphate (t-CPPD). A calcium pyrophosphate intermediate is first prepared by reaction of potassium pyrophosphate and calcium chloride. Samples of the intermediate are dissolved in hydrochloric acid and urea added. Upon heating to 95-100 degrees C, hydrolysis of the urea causes the pH to rise and t-CPPD crystallises out. Purity of the product was ascertained by chemical and physical analysis. Where large crystals are required an unstirred system is used, while smaller crystals are produced by stirring the reaction mixture.
引用
收藏
页码：1355 / 1360
页数：6
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