CANCER A precision approach to tumour treatment

被引：26
作者：
Dienstmann, Rodrigo [1 ,2 ]
Tabernero, Josep [3 ]
机构：
[1] Vall dHebron Inst Oncol, Barcelona 08035, Spain
[2] Sage Bionetworks, Seattle, WA 98109 USA
[3] Univ Autonoma Barcelona, Vall dHebron Univ Hosp, Dept Med Oncol, Barcelona 08035, Spain
来源：
NATURE | 2017年 / 548卷 / 7665期
关键词：
COLORECTAL-CANCER; MEDICINE; MODELS;
D O I：
10.1038/nature23101
中图分类号：
O [数理科学和化学]; P [天文学、地球科学]; Q [生物科学]; N [自然科学总论];
学科分类号：
07 ; 0710 ; 09 ;
摘要：
Progress is being made in the use of personalized approaches to create both in vitro and in vivo tumour models that could be used to aid cancer drug-treatment decisions and increase our understanding of how tumours respond to therapy.
引用
收藏
页码：40 / 41
页数：2
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  • [1] Colonic organoids derived from human induced pluripotent stem cells for modeling colorectal cancer and drug testing
    Crespo, Miguel
    Vilar, Eduardo
    Tsai, Su-Yi
    Chang, Kyle
    Amin, Sadaf
    Srinivasan, Tara
    Zhang, Tuo
    Pipalia, Nina H.
    Chen, Huanhuan Joyce
    Witherspoon, Mavee
    Gordillo, Miriam
    Xiang, Jenny Zhaoying
    Maxfield, Frederick R.
    Lipkin, Steven
    Evans, Todd
    Chen, Shuibing
    [J]. NATURE MEDICINE, 2017, 23 (07) : 878 - +
  • [2] High-Throughput Genomics and Clinical Outcome in Hard-to-Treat Advanced Cancers: Results of the MOSCATO 01 Trial
    Massard, Christophe
    Michiels, Stefan
    Ferte, Charles
    Le Deley, Marie-Cecile
    Lacroix, Ludovic
    Hollebecque, Antoine
    Verlingue, Loic
    Ileana, Ecaterina
    Rosellini, Silvia
    Ammari, Samy
    Ngo-Camus, Maud
    Bahleda, Rastislav
    Gazzah, Anas
    Varga, Andrea
    Postel-Vinay, Sophie
    Loriot, Yohann
    Even, Caroline
    Breuskin, Ingrid
    Auger, Nathalie
    Job, Bastien
    De Baere, Thierry
    Deschamps, Frederic
    Vielh, Philippe
    Scoazec, Jean-Yves
    Lazar, Vladimir
    Richon, Catherine
    Ribrag, Vincent
    Deutsch, Eric
    Angevin, Eric
    Vassal, Gilles
    Eggermont, Alexander
    Andre, Fabrice
    Soria, Jean-Charles
    [J]. CANCER DISCOVERY, 2017, 7 (06) : 586 - 595
  • [3] Personalized In Vitro and In Vivo Cancer Models to Guide Precision Medicine
    Pauli, Chantal
    Hopkins, Benjamin D.
    Prandi, Davide
    Shaw, Reid
    Fedrizzi, Tarcisio
    Sboner, Andrea
    Sailer, Verena
    Augello, Michael
    Puca, Loredana
    Rosati, Rachele
    McNary, Terra J.
    Churakova, Yelena
    Cheung, Cynthia
    Triscott, Joanna
    Pisapia, David
    Rao, Rema
    Mosquera, Juan Miguel
    Robinson, Brian
    Faltas, Bishoy M.
    Emerling, Brooke E.
    Gadi, Vijayakrishna K.
    Bernard, Brady
    Elemento, Olivier
    Beltran, Himisha
    Demichelis, Francesca
    Kemp, Christopher J.
    Grandori, Carla
    Cantley, Lewis C.
    Rubin, Mark A.
    [J]. CANCER DISCOVERY, 2017, 7 (05) : 462 - 477
  • [4] Individualized Systems Medicine Strategy to Tailor Treatments for Patients with Chemorefractory Acute Myeloid Leukemia
    Pemovska, Tea
    Kontro, Mika
    Yadav, Bhagwan
    Edgren, Henrik
    Eldfors, Samuli
    Szwajda, Agnieszka
    Almusa, Henrikki
    Bespalov, Maxim M.
    Ellonen, Pekka
    Elonen, Erkki
    Gjertsen, Bjorn T.
    Karjalainen, Riikka
    Kulesskiy, Evgeny
    Lagstrom, Sonja
    Lehto, Anna
    Lepisto, Maija
    Lundan, Tuija
    Majumder, Muntasir Mamun
    Marti, Jesus M. Lopez
    Mattila, Pirkko
    Murumagi, Astrid
    Mustjoki, Satu
    Palva, Aino
    Parsons, Alun
    Pirttinen, Tero
    Ramet, Maria E.
    Suvela, Minna
    Turunen, Laura
    Vastrik, Imre
    Wolf, Maija
    Knowles, Jonathan
    Aittokallio, Tero
    Heckman, Caroline A.
    Porkka, Kimmo
    Kallioniemi, Olli
    Wennerberg, Krister
    [J]. CANCER DISCOVERY, 2013, 3 (12) : 1416 - 1429
  • [5] Molecular dissection of colorectal cancer in pre-clinical models identifies biomarkers predicting sensitivity to EGFR inhibitors
    Schuette, Moritz
    Risch, Thomas
    Abdavi-Azar, Nilofar
    Boehnke, Karsten
    Schumacher, Dirk
    Keil, Marlen
    Yildirimman, Reha
    Jandrasits, Christine
    Borodina, Tatiana
    Amstislavskiy, Vyacheslav
    Worth, Catherine L.
    Schweiger, Caroline
    Liebs, Sandra
    Lange, Martin
    Warnatz, Hans-Joerg
    Butcher, Lee M.
    Barrett, James E.
    Sultan, Marc
    Wierling, Christoph
    Golob-Schwarzl, Nicole
    Lax, Sigurd
    Uranitsch, Stefan
    Becker, Michael
    Welte, Yvonne
    Regan, Joseph Lewis
    Silvestrov, Maxine
    Kehler, Inge
    Fusi, Alberto
    Kessler, Thomas
    Herwig, Ralf
    Landegren, Ulf
    Wienke, Dirk
    Nilsson, Mats
    Velasco, Juan A.
    Garin-Chesa, Pilar
    Reinhard, Christoph
    Beck, Stephan
    Schaefer, Reinhold
    Regenbrecht, Christian R. A.
    Henderson, David
    Lange, Bodo
    Haybaeck, Johannes
    Keilholz, Ulrich
    Hoffmann, Jens
    Lehrach, Hans
    Yaspo, Marie-Laure
    [J]. NATURE COMMUNICATIONS, 2017, 8
  • [6] Prospective Derivation of a Living Organoid Biobank of Colorectal Cancer Patients
    van de Wetering, Marc
    Francies, Hayley E.
    Francis, Joshua M.
    Bounova, Gergana
    Iorio, Francesco
    Pronk, Apollo
    van Houdt, Winan
    van Gorp, Joost
    Taylor-Weiner, Amaro
    Kester, Lennart
    McLaren-Douglas, Anne
    Blokker, Joyce
    Jaksani, Sridevi
    Bartfeld, Sina
    Volckman, Richard
    van Sluis, Peter
    Li, Vivian S. W.
    Seepo, Sara
    Pedamallu, Chandra Sekhar
    Cibulskis, Kristian
    Carter, Scott L.
    McKenna, Aaron
    Lawrence, Michael S.
    Lichtenstein, Lee
    Stewart, Chip
    Koster, Jan
    Versteeg, Rogier
    van Oudenaarden, Alexander
    Saez-Rodriguez, Julio
    Vries, Robert G. J.
    Getz, Gad
    Wessels, Lodewyk
    Stratton, Michael R.
    McDermott, Ultan
    Meyerson, Matthew
    Garnett, Mathew J.
    Clevers, Hans
    [J]. CELL, 2015, 161 (04) : 933 - 945
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