Renal effects of renin-angiotensin system blockade

被引:9
作者
Franco, M [1 ]
Paniagua, R [1 ]
Herrera-Acosta, J [1 ]
机构
[1] Inst Nacl Cardiol Ignacio Chavez, Dept Nephrol, Mexico City 14080, DF, Mexico
关键词
D O I
10.1097/00041552-199803000-00003
中图分类号
R5 [内科学]; R69 [泌尿科学(泌尿生殖系疾病)];
学科分类号
1002 ; 100201 ;
摘要
Pharmacological interruption of the renin-angiotensin system at different pathway levels has extended our knowledge on the distribution of angiotensin receptors in different nephron segments, its regulation and tubular cell responses. Novel beneficial effects obtained with blockade of this peptide on cellular proliferation and its interaction with other vasoactive systems are particularly important for preventing renal damage. (C) 1998 Rapid Science Ltd.
引用
收藏
页码:153 / 158
页数:6
相关论文
共 44 条
[31]   Regulation of angiotensin II receptor AT(1) subtypes in renal afferent arterioles during chronic changes in sodium diet [J].
Ruan, XP ;
Wagner, C ;
Chatziantoniou, C ;
Kurtz, A ;
Arendshorst, WJ .
JOURNAL OF CLINICAL INVESTIGATION, 1997, 99 (05) :1072-1081
[32]   Enalaprilat inhibits hydrogen peroxide production by murine mesangial cells exposed to high glucose concentrations [J].
RuizMunoz, LM ;
VidalVanaclocha, F ;
Lampreabe, I .
NEPHROLOGY DIALYSIS TRANSPLANTATION, 1997, 12 (03) :456-464
[33]   Tissue-specific regulation of type 1 angiotensin II receptor mRNA levels in the rat [J].
Sechi, LA ;
Griffin, CA ;
Giacchetti, G ;
Valentin, JP ;
LlorensCortes, C ;
Corvol, P ;
Schambelan, M .
HYPERTENSION, 1996, 28 (03) :403-408
[34]   INCREASED GLOMERULAR CAPILLARY-PRESSURE ALTERS GLOMERULAR CYTOKINE EXPRESSION [J].
SHANKLAND, SJ ;
LY, H ;
THAI, K ;
SCHOLEY, JW .
CIRCULATION RESEARCH, 1994, 75 (05) :844-853
[35]   Renin-angiotensin system modulates renal bradykinin production [J].
Siragy, HM ;
Jaffa, AA ;
Margolius, HS ;
Carey, RM .
AMERICAN JOURNAL OF PHYSIOLOGY-REGULATORY INTEGRATIVE AND COMPARATIVE PHYSIOLOGY, 1996, 271 (04) :R1090-R1095
[36]   Effects of an angiotensin-converting enzyme inhibitor, a calcium antagonist, and an endothelin receptor antagonist on renal afferent arteriolar structure [J].
Skov, K ;
FengerGron, J ;
Mulvany, MJ .
HYPERTENSION, 1996, 28 (03) :464-471
[37]   PCR LOCALIZATION OF ANGIOTENSIN-II RECEPTOR AND ANGIOTENSINOGEN MESSENGER-RNAS IN RAT-KIDNEY [J].
TERADA, Y ;
TOMITA, K ;
NONOGUCHI, H ;
MARUMO, F .
KIDNEY INTERNATIONAL, 1993, 43 (06) :1251-1259
[38]  
Unger T, 1996, J HYPERTENS, V14, pS95
[39]  
Valentin JP, 1997, AM J HYPERTENS, V10, P397
[40]   Regulation of type 1 angiotensin II receptor and its subtype gene expression in kidney by sodium loading and angiotensin II infusion [J].
Wang, DH ;
Du, Y ;
Yao, AQ ;
Hu, ZY .
JOURNAL OF HYPERTENSION, 1996, 14 (12) :1409-1415