The potential of ordered mesoporous silica for the storage of drugs:: The example of a pentapeptide encapsulated in a MSU-Tween 80

被引：85

作者：

Tourné-Péteilh, C

Lerner, DA

Charnay, C

Nicole, L

Bégu, S

Devoisselle, JM

机构：

[1] Ecole Natl Super Chim, CNRS, UMR 5618, ENSCM, F-34296 Montpellier, France

[2] CNRS, UMR 5618, ENSCM, F-34060 Montpellier, France

[3] Univ Montpellier I, F-34060 Montpellier, France

来源：

CHEMPHYSCHEM | 2003年 / 4卷 / 03期

关键词：

adsorption; drug delivery; mesoporous materials; pentagastrin; UV/Vis spectroscopy;

D O I：

10.1002/cphc.200390045

中图分类号：

O64 [物理化学（理论化学）、化学物理学];

学科分类号：

070304 ; 081704 ;

摘要：

Checking the dosage! Carrying a drug adsorbed on a mesoporous silica material may become a standard to deliver drugs. But how can you be sure that the drug is safely tucked inside the channels (see graphic)? The authors tackle this tricky problem.

引用

页码：281 / +

页数：7

共 47 条

[1] Growth of quantum-confined indium phosphide inside MCM-41 [J].

Agger, JR ;

Anderson, MW ;

Pemble, ME ;

Terasaki, O ;

Nozue, Y .

JOURNAL OF PHYSICAL CHEMISTRY B, 1998, 102 (18) :3345-3353

[2] Synthesis of macro-mesoporous niobium oxide molecular sieves by a ligand-assisted vesicle templating strategy [J].

Antonelli, DM .

MICROPOROUS AND MESOPOROUS MATERIALS, 1999, 33 (1-3) :209-214

[3] THE DETERMINATION OF PORE VOLUME AND AREA DISTRIBUTIONS IN POROUS SUBSTANCES .1. COMPUTATIONS FROM NITROGEN ISOTHERMS [J].

BARRETT, EP ;

JOYNER, LG ;

HALENDA, PP .

JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, 1951, 73 (01) :373-380

[4] A NEW FAMILY OF MESOPOROUS MOLECULAR-SIEVES PREPARED WITH LIQUID-CRYSTAL TEMPLATES [J].

BECK, JS ;

VARTULI, JC ;

ROTH, WJ ;

LEONOWICZ, ME ;

KRESGE, CT ;

SCHMITT, KD ;

CHU, CTW ;

OLSON, DH ;

SHEPPARD, EW ;

MCCULLEN, SB ;

HIGGINS, JB ;

SCHLENKER, JL .

JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, 1992, 114 (27) :10834-10843

[5] A new synthesis of mesoporous MSU-X silica controlled by a two-step pathway [J].

Boissière, C ;

Larbot, A ;

van der Lee, A ;

Kooyman, PJ ;

Prouzet, E .

CHEMISTRY OF MATERIALS, 2000, 12 (10) :2902-2913

[6]

Brown JA, 1997, NEUROSURG CLIN N AM, V8, P1

[7] On a theory of the van der Waals adsorption of gases [J].

Brunauer, S ;

Deming, LS ;

Deming, WE ;

Teller, E .

JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, 1940, 62 :1723-1732

[8] Chiral mesoporous hybrid organic-inorganic materials in enantioselective catalysis [J].

Brunel, D .

SUPPORTED CATALYSTS AND THEIR APPLICATIONS, 2001, (266) :38-47

[9] Tryptophan fluorescence shifts in proteins from hybrid simulations: An electrostatic approach [J].

Callis, PR ;

Burgess, BK .

JOURNAL OF PHYSICAL CHEMISTRY B, 1997, 101 (46) :9429-9432

[10]

Callis PR, 1997, METHOD ENZYMOL, V278, P113

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