Medicinal Plants, Phytochemicals, and Herbs to Combat Viral Pathogens Including SARS-CoV-2

被引：59

作者：

Anand, Arumugam Vijaya ^{[1
]}

Balamuralikrishnan, Balasubramanian ^{[2
]}

Kaviya, Mohandass ^{[1
]}

Bharathi, Kathirvel ^{[1
]}

Parithathvi, Aluru ^{[1
]}

Arun, Meyyazhagan ^{[3
]}

Senthilkumar, Nachiappan ^{[4
]}

Velayuthaprabhu, Shanmugam ^{[5
]}

Saradhadevi, Muthukrishnan ^{[6
]}

Al-Dhabi, Naif Abdullah ^{[7
]}

Arasu, Mariadhas Valan ^{[7
,8
]}

Yatoo, Mohammad Iqbal ^{[9
]}

Tiwari, Ruchi ^{[10
]}

Dhama, Kuldeep ^{[11
]}

机构：

[1] Bharathiar Univ, Dept Human Genet & Mol Biol, Med Genet & Epigenet Lab, Coimbatore 641046, Tamil Nadu, India

[2] Sejong Univ, Coll Life Sci, Dept Food Sci & Biotechnol, Seoul 05006, South Korea

[3] CHRIST Deemed Univ, Dept Life Sci, Bengaluru 560029, India

[4] Inst Forest Genet & Tree Breeding IFGTB, Forest Campus,Cowley Brown Rd, Coimbatore 641002, Tamil Nadu, India

[5] Bharathiar Univ, Dept Biotechnol, Coimbatore 641046, Tamil Nadu, India

[6] Bharathiar Univ, Dept Biochem, Coimbatore 641046, Tamil Nadu, India

[7] King Saud Univ, Coll Sci, Dept Bot & Microbiol, POB 2455, Riyadh 11451, Saudi Arabia

[8] St Xaviers Coll, Xavier Res Fdn, Palayankottai 627002, Thirunelveli, India

[9] Sher E Kashmir Univ Agr Sci & Technol Kashmir, Fac Vet Sci & Anim Husb, Srinagar 190006, India

[10] UP Deen Dayal Upadhayay Pashu Chikitsa Vigyan Vis, Coll Vet Sci, Dept Vet Microbiol & Immunol, Mathura 281001, India

[11] ICAR Indian Vet Res Inst, Div Pathol, Bareilly 243122, Uttar Pradesh, India

来源：

MOLECULES | 2021年 / 26卷 / 06期

关键词：

COVID-19; medicinal plants; phytochemicals; herbs; antiviral agents; SARS-CoV-2; HERPES-SIMPLEX-VIRUS; TRADITIONAL CHINESE MEDICINE; REPLICATION IN-VITRO; V-ATPASE INHIBITOR; ANTIVIRAL ACTIVITY; INFLUENZA-A; NORDIHYDROGUAIARETIC ACID; HEPATITIS-B; CORONAVIRUS SARS-COV-2; STRUCTURAL FEATURES;

D O I：

10.3390/molecules26061775

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

The coronavirus disease 2019 (COVID-19) pandemic, caused by severe acute respiratory syndrome corona virus-2 (SARS-CoV-2), is the most important health issue, internationally. With no specific and effective antiviral therapy for COVID-19, new or repurposed antiviral are urgently needed. Phytochemicals pose a ray of hope for human health during this pandemic, and a great deal of research is concentrated on it. Phytochemicals have been used as antiviral agents against several viruses since they could inhibit several viruses via different mechanisms of direct inhibition either at the viral entry point or the replication stages and via immunomodulation potentials. Recent evidence also suggests that some plants and its components have shown promising antiviral properties against SARS-CoV-2. This review summarizes certain phytochemical agents along with their mode of actions and potential antiviral activities against important viral pathogens. A special focus has been given on medicinal plants and their extracts as well as herbs which have shown promising results to combat SARS-CoV-2 infection and can be useful in treating patients with COVID-19 as alternatives for treatment under phytotherapy approaches during this devastating pandemic situation.

引用

页数：28

共 214 条

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