Hypoxia, HIF1α and estrogen receptor

被引:0
|
作者
Massaad-Massade, L [1 ]
机构
[1] Univ Paris 05, INSERM U490, F-75270 Paris, France
关键词
estrogen receptor; hypoxia; signalisation pathways; treatment;
D O I
暂无
中图分类号
R73 [肿瘤学];
学科分类号
100214 ;
摘要
The estrogen receptor plays an important role in the development of hormone-dependent breast cancer. Experimental and clinical studies showed that hypoxia was involved in tumor progression and in the resistance to anticancer agents. The scope of this review is to summarize recent observations on these two signaling pathways and to show their importance and possible interaction in the development of hormone-dependent breast cancer.
引用
收藏
页码:677 / 683
页数:7
相关论文
共 50 条
  • [41] Transcriptional regulation of the lysyl oxidase gene by the hypoxia-inducible factor 1 (HIF1)
    Li, Wande
    Zhao, Yinzhi
    Gao, Song
    Toselli, Paul
    FASEB JOURNAL, 2010, 24
  • [42] Mir-199a is downregulated in hypoxia and targets HIF1α in ovarian cancer cells
    Josh, Hemant
    Subramanian, Indira
    Ghosh, Goutam
    Zeng, Yan
    Zhao, Min
    Ramakrishnan, Sundaram
    CANCER RESEARCH, 2010, 70
  • [43] A computational model of intracellular oxygen sensing by hypoxia-inducible factor HIF1α
    Qutub, Amina A.
    Popel, Aleksander S.
    JOURNAL OF CELL SCIENCE, 2006, 119 (16) : 3467 - 3480
  • [44] STAT3 and HIF1α cooperatively mediate the transcriptional and physiological responses to hypoxia
    Dinarello, Alberto
    Betto, Riccardo Massimiliano
    Diamante, Linda
    Tesoriere, Annachiara
    Ghirardo, Rachele
    Cioccarelli, Chiara
    Meneghetti, Giacomo
    Peron, Margherita
    Laquatra, Claudio
    Tiso, Natascia
    Martello, Graziano
    Argenton, Francesco
    CELL DEATH DISCOVERY, 2023, 9 (01)
  • [45] STAT3 and HIF1α cooperatively mediate the transcriptional and physiological responses to hypoxia
    Alberto Dinarello
    Riccardo Massimiliano Betto
    Linda Diamante
    Annachiara Tesoriere
    Rachele Ghirardo
    Chiara Cioccarelli
    Giacomo Meneghetti
    Margherita Peron
    Claudio Laquatra
    Natascia Tiso
    Graziano Martello
    Francesco Argenton
    Cell Death Discovery, 9
  • [46] Hypoxia compromises the mitochondrial metabolism of Alzheimer's disease microglia via HIF1
    March-Diaz, Rosana
    Lara-Urena, Nieves
    Romero-Molina, Carmen
    Heras-Garvin, Antonio
    Luis, Clara Ortega-de San
    Alvarez-Vergara, Maria, I
    Sanchez-Garcia, Manuel A.
    Sanchez-Mejias, Elisabeth
    Davila, Jose C.
    Rosales-Nieves, Alicia E.
    Forja, Cristina
    Navarro, Victoria
    Gomez-Arboledas, Angela
    Sanchez-Mico, Maria, V
    Viehweger, Adrian
    Gerpe, Almudena
    Hodson, Emma J.
    Vizuete, Marisa
    Bishop, Tammie
    Serrano-Pozo, Alberto
    Lopez-Barneo, Jose
    Berra, Edurne
    Gutierrez, Antonia
    Vitorica, Javier
    Pascual, Alberto
    NATURE AGING, 2021, 1 (04): : 385 - +
  • [47] Metabolic targeting of hypoxia and HIF1 in solid tumors can enhance cytotoxic chemotherapy
    Cairns, Rob A.
    Papandreou, Ioanna
    Sutphin, Patrick D.
    Denko, Nicholas C.
    PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 2007, 104 (22) : 9445 - 9450
  • [48] THE EFFECT OF HYPOXIA AND HYPERGLYCEMIA ON NOTCH AND HIF1α EXPRESSION IN HUMAN RENAL CORTICAL FIBROBLAST
    Sumual, S.
    Saad, S.
    Panchapakesan, U.
    Pollock, C.
    NEPHROLOGY, 2008, 13 : A137 - A138
  • [49] Hypoxia diminishes the expression of C/EBPα in breast cancer via HIF1α method
    Seifeddine, R.
    Dreiem, A.
    Mayi, T.
    Massaad-Massade, L.
    BULLETIN DU CANCER, 2007, 94 (06) : 536 - 536
  • [50] Hypoxia Induces Pro-Regenerative Activity of Renal Fibroblasts via Hif1α
    Zeisberg, Michael
    Nyamsuren, Gunsmaa
    JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY, 2022, 33 (11): : 629 - 630