Dobrava-Belgrade Virus Spillover Infections, Germany

被引:45
作者
Schlegel, Mathias [1 ]
Klempa, Boris [2 ,3 ]
Auste, Brita [2 ]
Bemmann, Margrit [4 ]
Schmidt-Chanasit, Jonas [5 ]
Buechner, Thomas [1 ]
Groschup, Martin H. [1 ]
Meier, Markus [6 ]
Balkema-Buschmann, Anne [1 ]
Zoller, Hinrich [7 ]
Krueger, Detlev H. [2 ]
Ulrich, Rainer G. [1 ]
机构
[1] Friedrich Loeffler Inst Inst Novel & Emerging Inf, Greifswald, Germany
[2] Charite, D-13353 Berlin, Germany
[3] Slovak Acad Sci, Bratislava, Slovakia
[4] Landesforstanstalt Mecklenburg Vorpommern, Schwerin, Germany
[5] Bernhard Nocht Inst Trop Med, Hamburg, Germany
[6] Med Univ Lubeck, D-23538 Lubeck, Germany
[7] Univ Rostock, Rostock, Germany
关键词
HEMORRHAGIC-FEVER; RENAL SYNDROME; CENTRAL-EUROPE; HANTAVIRUS; LINEAGES; SLOVENIA; RODENTS;
D O I
10.3201/eid1512.090923
中图分类号
R392 [医学免疫学]; Q939.91 [免疫学];
学科分类号
100102 ;
摘要
We present the molecular identification of Apodemus agrarius (striped field mouse) as reservoir host of the Dobrava-Belgrade virus (DOBV) lineage DOBV-Aa in 3 federal states of Germany. Phylogenetic analyses provided evidence for multiple spillover of DOBV-Aa to A. flavicollis, a crucial prerequisite for host switch and genetic reassortment.
引用
收藏
页码:2017 / 2020
页数:4
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