Postural Orthostatic Tachycardia Syndrome (POTS) - A novel member of the autoimmune family

被引:40
作者
Dahan, S. [1 ,2 ]
Tomljenovic, L. [3 ]
Shoenfeld, Y. [1 ,2 ]
机构
[1] Sheba Med Ctr, Zabludowicz Ctr Autoimmune Dis, Tel Hashomer, Israel
[2] Tel Aviv Univ, Sackler Fac Med, IL-69978 Tel Aviv, Israel
[3] Univ British Columbia, Fac Med, Vancouver, BC, Canada
关键词
Postural orthostatic tachycardia syndrome (POTS); chronic fatigue syndrome (CFS); autoimmunity; autoantibodies; molecular mimicry; human papilloma virus (HPV); CHRONIC-FATIGUE-SYNDROME; RIGHT-VENTRICULAR DYSPLASIA/CARDIOMYOPATHY; AUTONOMIC DYSFUNCTION; INTOLERANCE; PROTEIN; AUTOANTIBODIES; ANTINUCLEAR; ANTIBODIES; MUTATIONS; ADJUVANTS;
D O I
10.1177/0961203316629558
中图分类号
R5 [内科学];
学科分类号
1002 ; 100201 ;
摘要
Postural orthostatic tachycardia syndrome (POTS) is a heterogeneous disorder of the autonomic nervous system in which a change from the supine position to an upright position causes an abnormally large increase in heart rate or tachycardia (30 bpm within 10 min of standing or head-up tilt). This response is accompanied by a decrease in blood flow to the brain and hence a spectrum of symptoms associated with cerebral hypoperfusion.(1) Many of these POTS-related symptoms are also observed in chronic anxiety and panic disorders, and therefore POTS is frequently under-and misdiagnosed.(2,3)
引用
收藏
页码:339 / 342
页数:4
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