Arylthioureas with bromine or its equivalents gives no 'Hugerschoff' reaction product

被引：16

作者：

Yella, Ramesh ^{[1
]}

Murru, Siva ^{[1
]}

Ali, Abdur Rezzak ^{[1
]}

Patel, Bhisma K. ^{[1
]}

机构：

[1] Indian Inst Technol Guwahati, Gauhati 781039, Assam, India

来源：

ORGANIC & BIOMOLECULAR CHEMISTRY | 2010年 / 8卷 / 15期

关键词：

ONE-POT SYNTHESIS; 1,1'-(ETHANE-1,2-DIYL)DIPYRIDINIUM BISTRIBROMIDE EDPBT; TETRABUTYLAMMONIUM TRIBROMIDE TBATB; EFFICIENT CHEMOSELECTIVE REAGENT; 1,3-DISUBSTITUTED THIOUREAS; CARBONYL-COMPOUNDS; ACETALIZATION; THIOACETALIZATION; CONVERSION; ACYLATION;

D O I：

10.1039/c003892j

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

The in situ generated aryl-alkyl unsymmetrical thiourea obtained by the reaction of an aryl isothiocyanate with an aliphatic secondary amine on treatment with bromine or its equivalent gave exclusively a product having a thioamido guanidino moiety and not the expected Hugerschoff product 2-aminobenzothiazole. A plausible reaction mechanism has been proposed for this unprecedented transformation and the scope has been extended to various substrates.

引用

页码：3389 / 3393

页数：5

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