First total synthesis of (±)-AM6898A by stereoselective aldol cyclization

被引：4

作者：

Fukuda, Y ^{[1
]}

Sakurai, M ^{[1
]}

Okamoto, Y ^{[1
]}

机构：

[1] Eisai & Co Ltd, Tsukuba Res Labs, Tsukuba, Ibaraki 3002635, Japan

来源：

TETRAHEDRON LETTERS | 2000年 / 41卷 / 44期

关键词：

D O I：

10.1016/S0040-4039(00)01539-2

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

First total synthesis of (+/-)-AM6898A has been achieved by stereoselective aldol cyclization via a thermodynamically controlled condition. (C) 2000 Elsevier Science Ltd. All rights reserved.

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页码：8505 / 8508

页数：4

相关论文

共 4 条

[1] First total synthesis of (±)-AM6898D and its three diastereoisomers by Claisen rearrangement and stereoselective epimerization
Fukuda, Y
Sakurai, M
Okamoto, Y
[J]. TETRAHEDRON LETTERS, 2000, 41 (21) : 4173 - 4175
[2] TOTAL SYNTHESIS OF VERNOLEPIN .1. SYNTHESIS OF THE KEY INTERMEDIATE
IIO, H
ISOBE, M
KAWAI, T
GOTO, T
[J]. TETRAHEDRON, 1979, 35 (08) : 941 - 948
[3] STERIC INTERFERENCE IN ALLYLIC AND PSEUDO-ALLYLIC SYSTEMS .2. STEREOCHEMISTRY OF EXOCYCLIC ENOLATE ANION PROTONATION
MALHOTRA, SK
JOHNSON, F
[J]. JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, 1965, 87 (23) : 5493 - &
[4] Yaginuma A, 1997, Patent No. [09309859, Japanese Patent, JP]