Clinical Trial Registration Patterns and Changes in Primary Outcomes of Randomized Clinical Trials From 2002 to 2017

被引：6

作者：

Lamberink, Herm J. ^{[1
,2
]}

Vinkers, Christiaan H. ^{[3
,4
]}

Lancee, Michelle ^{[5
]}

Damen, Johanna A. A. ^{[6
]}

Bouter, Lex M. ^{[7
,8
]}

Otte, Willem M. ^{[2
,9
]}

Tijdink, Joeri K. ^{[8
,10
]}

机构：

[1] Haaglanden Med Ctr, Dept Neurol, The Hague, Netherlands

[2] Univ Med Ctr UMC Utrecht, Dept Child Neurol, UMC Utrecht Brain Ctr, Utrecht, Netherlands

[3] Vrije Univ, Dept Psychiat, Amsterdam Univ Med Ctr, Amsterdam Neurosci, Amsterdam, Netherlands

[4] Vrije Univ, Dept Anat & Neurosci, Amsterdam Univ Med Ctr, Amsterdam Neurosci, Amsterdam, Netherlands

[5] Univ Med Ctr Utrecht, Dept Psychiat, UMC Utrecht Brain Ctr, Utrecht, Netherlands

[6] Univ Utrecht, Cochrane Netherlands, Julius Ctr Hlth Sci & Primary Care, Univ Med Ctr Utrecht, Utrecht, Netherlands

[7] Amsterdam Univ Med Ctr, Dept Epidemiol & Data Sci, Amsterdam, Netherlands

[8] Vrije Univ, Dept Philosophy, Fac Humanities, Amsterdam, Netherlands

[9] Univ Med Ctr Utrecht, Biomed MR Imaging & Spect, Ctr Image Sci, Utrecht, Netherlands

[10] Amsterdam Univ Med Ctr, Dept Eth Law & Humanities, Locat VUmc, De Boelelaan 1117, NL-1081 HZ Amsterdam, Netherlands

来源：

JAMA INTERNAL MEDICINE | 2022年 / 182卷 / 07期

关键词：

D O I：

10.1001/jamainternmed.2022.1551

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

This cross-sectional study evaluates the existence and timing of trial registration for randomized clinical trials (RCTs) published from 2002 to 2017 as well as substantive changes to the primary outcomes entered into registry information after those studies started.

引用

页码：779 / 782

页数：4

共 6 条

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[3] The preregistration revolution
Nosek, Brian A.
Ebersole, Charles R.
DeHaven, Alexander C.
Mellor, David T.
[J]. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 2018, 115 (11) : 2600 - 2606
[4] Otte, FOSTERING RESPONSIBL
[5] Ramagopalan Sreeram, 2014, F1000Res, V3, P77, DOI 10.12688/f1000research.3784.1
[6] Update on Trial Registration 11 Years after the ICMJE Policy Was Established
Zarin, Deborah A.
Tse, Tony
Williams, Rebecca J.
Rajakannan, Thiyagu
[J]. NEW ENGLAND JOURNAL OF MEDICINE, 2017, 376 (04) : 383 - 391

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