Stereospecific synthesis of 2-acyl-4-alkyl-3-aryl-2,3,3a,4-tetrahydroindeno[1,2-c]pyrazoles

被引：0

作者：

Trimeche, B

Gharbi, R

Mighri, Z ^{[1
]}

Martin, MT

机构：

[1] Fac Sci Monastir, Lab Chim Subst Nat & Synth Organ, Monastir 5000, Tunisia

[2] CNRS, Inst Chim Subst Nat, F-91190 Gif Sur Yvette, France

来源：

HETEROCYCLIC COMMUNICATIONS | 2002年 / 8卷 / 05期

关键词：

D O I：

暂无

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

Stereospecific synthesis of trans-2-acyl-4-alkyl-3-aryl-2,3,3a,4-tetrahydroindeno[1,2-c]pyrazoles 3 has been performed by the two-steps reaction between 3-alkyl-2-arylidene-1-indanones 1 and hydrazine followed by acylation of the pyrazolenic intermediate 2. Structure and stereochemistry of compounds 3 have been elucidated by. IR measurements and NMR techniques : monodimensional : H-1, C-13; two-dimensional homonuclear H-1-H-1 (COSY, NOESY) and two-dimensional heteronuclear H-1-C-13 (HMQC, HMBC).

引用

页码：473 / 478

页数：6

共 50 条

[1] Synthesis and biological evaluation of novel 6, 7-dimethoxy-3-(4-pyridyl)-2,3,3a, 4-tetrahydroindeno[1,2-c]pyrazol-2-yl-4-substituted phenylmethanone/ethanone derivatives
Ali, Mohamed Ashraf
Ismail, Rusli
Choon, Tan Soo
Elumalai, Manogaran
Kumar, Suresh
Osman, Hasnah
Govidasamy, Jeyabalan
Yadav, Rajesh
Yadav, Garima
Kour, Ravinder
Vyas, Swati
JOURNAL OF ENZYME INHIBITION AND MEDICINAL CHEMISTRY, 2012, 27 (01) : 155 - 159
[2] SYNTHESIS OF 3,3A-TRANS/CIS-2-PHENYL/ACETYL-3-ARYL-TETRAHYDROINDENO/NAPHTHO[1,2-C]PYRAZOLES AND HEXAHYDROBENZO[6,7]CYCLOHEPTA[1,2-C]PYRAZOLES AS ANTIIMPLANTATION AGENTS
SINHA, AK
RASTOGI, SN
INDIAN JOURNAL OF CHEMISTRY SECTION B-ORGANIC CHEMISTRY INCLUDING MEDICINAL CHEMISTRY, 1991, 30 (07): : 684 - 692
[3] 2,3,3a,4,5,9b-hexahydro-4-phenylfuro-[3,2-c]quinoline
Ravikumar, K
Sridhar, B
Mahesh, M
Reddy, VVN
ACTA CRYSTALLOGRAPHICA SECTION E-CRYSTALLOGRAPHIC COMMUNICATIONS, 2006, 62 : O542 - O544
[4] A Simple Efficient Procedure for the Stereoselective Synthesis of trans-2,3,3a,4-Tetrahydro-3-aryl-2-(4-carboxyphenyl)[1]benzopyrano[4,3-c]pyrazoles and their [1]Benzothiopyrano Analogues
Levai, Albert
Jeko, Jozsef
ACTA CHIMICA SLOVENICA, 2009, 56 (03) : 566 - 570
[5] HETEROCYCLES .17. SYNTHESIS OF NEW SUBSTITUTED 2,3,3A,4,5,6-HEXAHYDROBENZO[6,7]CYCLOHEPTA[1,2-C]PYRAZOLES AND RELATED-COMPOUNDS
ELRAYYES, NR
BAHTITI, NH
JOURNAL OF HETEROCYCLIC CHEMISTRY, 1989, 26 (01) : 209 - 214
[6] SYNTHESIS AND ANTIMICROBIAL ACTIVITY OF SOME 6-ARYLIDENE-3-ARYL-2,3,3a,4,5,6-HEXAHYDROCYCLOPENTA [c] PYRAZOLES/OXAZOLES
Azam, Md. Afzal
Gomathy, S.
Alam, F.
Suresh, B.
INDIAN JOURNAL OF HETEROCYCLIC CHEMISTRY, 2008, 18 (02) : 157 - 160
[7] 4-(4-Nitrophenyl)-2,3,3a,4,5,9b-hexahydrofuro[3,2-c]quinoline
Ravikumar, K
Sridhar, B
Mahesh, M
Reddy, VVN
ACTA CRYSTALLOGRAPHICA SECTION E-CRYSTALLOGRAPHIC COMMUNICATIONS, 2005, 61 : O1419 - O1421
[8] SYNTHESIS OF 1-PHENYL-3-ARYL-[1]BENZOFURANO[3,2-C]-PYRAZOLES
JOSHI, MG
WADODKAR, KN
INDIAN JOURNAL OF CHEMISTRY SECTION B-ORGANIC CHEMISTRY INCLUDING MEDICINAL CHEMISTRY, 1981, 20 (10): : 930 - 931
[9] 4-(4-Bromophenyl)-2,3,3a,4,5,11c-hexahydrobenzo[f]furo[3,2-c]quinoline
Wu, Nan
Zhang, Rongli
Li, Xinnian
Xu, Xin
Xu, Zhou
ACTA CRYSTALLOGRAPHICA SECTION E-STRUCTURE REPORTS ONLINE, 2011, 67 : O2285 - U2200
[10] Fused heterocycles. 8 [1]. An efficient procedure for the stereoselective synthesis of trans-2,3,3a,4-tetrahydro-3-aryl-2-phenyl[1]benzopyrano[4,3-c]pyrazoles and their [1]benzothiopyrano analogues
Levai, A
JOURNAL OF HETEROCYCLIC CHEMISTRY, 1998, 35 (01) : 13 - 16

← 1 2 3 4 5 →