The potential role of cannabinoids in dermatology

被引:80
作者
Sheriff, Tabrez [1 ]
Lin, Matthew J. [2 ]
Dubin, Danielle [2 ]
Khorasani, Hooman [2 ]
机构
[1] Royal Prince Alfred Hosp, 50 Missenden Rd, Sydney, NSW, Australia
[2] Icahn Sch Med Mt Sinai, New York, NY 10029 USA
关键词
Cannabinoids in dermatology; cannabis; endocannabinoids; cannabidiol; ALLERGIC CONTACT-DERMATITIS; ATOPIC-DERMATITIS; ENDOCANNABINOID SYSTEM; SKIN; RECEPTORS; KERATINOCYTES; ANGIOGENESIS; INFLAMMATION; ACTIVATION; ANANDAMIDE;
D O I
10.1080/09546634.2019.1675854
中图分类号
R75 [皮肤病学与性病学];
学科分类号
100206 ;
摘要
Cannabis is increasingly being used world-wide to treat a variety of dermatological conditions. Medicinal cannabis is currently legalized in Canada, 31 states in America and 19 countries in Europe. The authors reviewed the literature on the pharmacology and use of cannabinoids in treating a variety of skin conditions including acne, atopic dermatitis, psoriasis, skin cancer, pruritus, and pain. Cannabinoids have demonstrated anti-inflammatory, antipruritic, anti-ageing, and antimalignancy properties by various mechanisms including interacting with the newly found endocannabinoid system of the skin thereby providing a promising alternative to traditional treatments.
引用
收藏
页码:839 / 845
页数:7
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