Study of ALA and small dosage of HPD photodynamic therapy (HPD-PDT) in treatment of skin cancer

被引：0

作者：

Lu, Wei ^{[1
]}

Feng, Wei ^{[2
]}

Tang, Yi ^{[1
]}

Tao, Xiaohua ^{[1
]}

Pan, Lei ^{[2
]}

机构：

[1] Zhejiang Prov Peoples Hosp, Dept Dermatol, Hangzhou, Zhejiang, Peoples R China

[2] Zhejiang Prov Peoples Hosp, Dept Plast & Reconstruct Surg, Hangzhou, Zhejiang, Peoples R China

来源：

BIOMEDICAL RESEARCH-INDIA | 2017年 / 28卷 / 14期

关键词：

Aminolevulinic acid (ALA); Hematoporphyrin derivative (FPD); Photodynamic therapy (PDT); Skin cancer; 5-AMINOLEVULINIC ACID;

D O I：

暂无

中图分类号：

R318 [生物医学工程];

学科分类号：

0831 ;

摘要：

Objective: To investigate clinical effect of ALA and small dosage of HPD-PDT in treatment of patients with skin cancer. Methods: From June 2014 to April 2017, 62 cases of malignant skin tumor patients treated in our hospital were selected as the objects and randomly divided into study group (31 cases) and control group (31 cases), respectively treated by ALA and small dosage of HPD-PDT and conventional HPD-PDT. The clinical effective rate and recurrence incidence in the two groups were compared to explore therapeutic effect of ALA and small dosage of HPD-PDT on skin cancers of different types. Results: The effective rate of the study group (100%) was significantly higher than that of the control group (87.09%) while the recurrence rate of the study group (3.23%) was significantly lower than that of the control group (19.35%) of statistical significance, P<0.05. Besides, the study group has more significant effects in treatment of skin cancers like adnexal tumor, basal cell carcinoma, malignant melanoma and squamous cell carcinoma. Conclusion: The clinical effect of ALA and small dosage of HPD-PDT has significant curative effects in the treatment of various skin tumors.

引用

页码：6476 / 6479

页数：4

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