Oxford-AstraZeneca COVID-19 vaccine: need of a reasoned and effective vaccine campaign

被引：10
|
作者：
Vallee, A. [1 ]
Chan-Hew-Wai, A. [2 ]
Bonan, B. [2 ]
Lesprit, P. [3 ]
Parquin, F. [4 ]
Catherinot, E. [5 ]
Choucair, J. [5 ]
Billard, D. [6 ]
Amiel-Taieb, C. [7 ]
Camps, E. [2 ]
Cerf, C. [8 ]
Zucman, D. [9 ]
Fourn, E. [9 ]
机构：
[1] Foch Hosp, Dept Clin Res & Innovat, Suresnes, France
[2] Foch Hosp, Hosp Pharm, Suresnes, France
[3] Foch Hosp, Dept Hyg & Infect Dis, Suresnes, France
[4] Foch Hosp, Intens Resp Care Dept, Suresnes, France
[5] Foch Hosp, Dept Pneumol, Suresnes, France
[6] Foch Hosp, Dept Oncol, Suresnes, France
[7] Foch Hosp, Dept Occupat Hlth, Suresnes, France
[8] Foch Hosp, Dept Intens Care, Suresnes, France
[9] Foch Hosp, Dept Internal Med, Reseau Ville Hop Val Seine, Suresnes, France
来源：
PUBLIC HEALTH | 2021年 / 196卷
关键词：
COVID-19; vaccine; AstraZeneca vaccine; Adverse effects; Vaccine campaign;
D O I：
10.1016/j.puhe.2021.05.030
中图分类号：
R1 [预防医学、卫生学];
学科分类号：
1004 ; 120402 ;
摘要：
Objectives: A strong COVID-19 vaccine campaign is needed to reach the herd immunity and reduce this pandemic infection. Study design: In the Foch Hospital, France, in February 2021, 451 healthcare workers were vaccinated by a first dose of AstraZeneca vaccine. Methods: Adverse effects were reported to our pharmaco-vigilance circuit, by an online and anonymous questionnaire following the first weeks of the vaccinal campaign to healthcare workers. Results: Two hundred seventy-four (60.8%) of them reported multiple adverse effects. Main adverse effects reported were feverish state/chills (65.7%), fatigue/physical discomfort (62.4%), arthralgia/muscle pain (61.0%) and fever (44.5%). Conclusions: On March 2021 many European countries suspended AstraZeneca vaccine for one week due to safety uncertainty. Thus, confidence in its efficacy is undermined. However, the benefit/risk balance is clearly in favor of vaccination. (C) 2021 The Royal Society for Public Health. Published by Elsevier Ltd. All rights reserved.
引用
收藏
页码：135 / 137
页数：3
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