Enhanced performance of Aloe vera incorporated chitosan-polyethylene oxide electrospun wound scaffold produced using novel Spirograph based collector assembly

被引：29

作者：

Pathalamuthu, P. ^{[1
]}

Siddharthan, A. ^{[2
]}

Giridev, V. R. ^{[3
]}

Victoria, Victor ^{[4
]}

Thangam, Ramar ^{[5
]}

Sivasubramanian, Srinivasan ^{[4
]}

Savariar, Vincent ^{[4
]}

Hemamalini, T. ^{[3
]}

机构：

[1] Anand Inst Higher Technol, Dept Mech Engn, Chennai, Tamil Nadu, India

[2] Anna Univ, Dept Prod Engn, Chennai, Tamil Nadu, India

[3] Anna Univ, Dept Text Technol, Chennai, Tamil Nadu, India

[4] Loyola Coll, LIFE, Ctr Environm Res & Dev, Chennai, Tamil Nadu, India

[5] CSIR Cent Leather Res Inst, Chennai, Tamil Nadu, India

来源：

INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES | 2019年 / 140卷

关键词：

Aloe vera; Chitosan; Electrospun mat; Mechanical property; Polyethylene oxide; Wound scaffold; MECHANICAL-PROPERTIES; NANOFIBERS; BEHAVIOR; MATS;

D O I：

10.1016/j.ijbiomac.2019.08.158

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

Spirograph is a geometric drawing that produces mathematical roulette curves of the variety technically known as hypotrochoids and epitrochoids. This paper presents a research on a novel Spirograph Based Mechanical System (SBMS) meant for the production of electrospun mat with near uniform characteristics for wound dressing applications. A combination of natural (Chitosan) and artificial (Polyethylene oxide) polymer, along with Aloe vera plant extract has been evaluated as a material for wound dressing application. The improvement in the mechanical property, in vitro and in vivo studies indicate developed SBMS compared to the typical collectors has been found suitable for producing electrospun mat for wound dressing applications. (C) 2019 Elsevier B.V. All rights reserved.

引用

页码：808 / 824

页数：17