Drive or reverse? A tripeptide transmission switch for gating CNG and HCN channels by cyclic nucleotide

被引:0
|
作者
Zhou, L
Olivier, NB
Siegelbaum, SA
机构
[1] Columbia Univ, Ctr Neurobiol & Behav, Howard Hughes Med Inst, New York, NY 10032 USA
[2] Columbia Univ, Dept Biochem & Mol Biophys, New York, NY 10032 USA
[3] Columbia Univ, Dept Pharmacol, New York, NY 10032 USA
关键词
D O I
暂无
中图分类号
Q6 [生物物理学];
学科分类号
071011 ;
摘要
引用
收藏
页码:20A / 20A
页数:1
相关论文
共 50 条
  • [1] A conserved tripeptide in CNG and HCN channels regulates ligand gating by controlling C-terminal oligomerization
    Zhou, L
    Olivier, NB
    Yao, H
    Young, EC
    Siegelbaum, SA
    NEURON, 2004, 44 (05) : 823 - 834
  • [2] Modulation of gating kinetics of hyperpolarizationactivated cyclic nucleotide-gated (HCN) channels by SRC kinase
    Zong, X
    Eckert, C
    Abicht, H
    Yuan, H
    Gerstner, A
    Much, B
    Wahl-Schott, C
    Chen, Z
    Biel, M
    NAUNYN-SCHMIEDEBERGS ARCHIVES OF PHARMACOLOGY, 2005, 371 : R50 - R51
  • [3] Novel Fluorescent Cyclic Nucleotide Derivatives to Study CNG and HCN Channel Function
    Otte, Maik
    Schweinitz, Andrea
    Lelle, Marco
    Thon, Susanne
    Enke, Uta
    Yueksel, Sezin
    Schmauder, Ralf
    Bonus, Michele
    Gohlke, Holger
    Benndorft, Klaus
    BIOPHYSICAL JOURNAL, 2019, 116 (12) : 2411 - 2422
  • [4] Cyclic Nucleotide Mapping of Hyperpolarization-Activated Cyclic Nucleotide-Gated (HCN) Channels
    Moeller, Stefan
    Alfieri, Andrea
    Bertinetti, Daniela
    Aquila, Marco
    Schwede, Frank
    Lolicato, Marco
    Rehmann, Holger
    Moroni, Anna
    Herberg, Friedrich W.
    ACS CHEMICAL BIOLOGY, 2014, 9 (05) : 1128 - 1137
  • [5] A novel dimerization interface of cyclic nucleotide binding domain, which is disrupted in presence of cAMP: implications for CNG channels gating
    Ivan Y. Gushchin
    Valentin I. Gordeliy
    Sergei Grudinin
    Journal of Molecular Modeling, 2012, 18 : 4053 - 4060
  • [6] A novel dimerization interface of cyclic nucleotide binding domain, which is disrupted in presence of cAMP: implications for CNG channels gating
    Gushchin, Ivan Y.
    Gordeliy, Valentin I.
    Grudinin, Sergei
    JOURNAL OF MOLECULAR MODELING, 2012, 18 (09) : 4053 - 4060
  • [7] The HCN domain couples voltage gating and cAMP response in hyperpolarization-activated cyclic nucleotide-gated channels
    Porro, Alessandro
    Saponaro, Andrea
    Gasparri, Federica
    Bauer, Daniel
    Gross, Christine
    Pisoni, Matteo
    Abbandonato, Gerardo
    Hamacher, Kay
    Santoro, Bina
    Thiel, Gerhard
    Moroni, Anna
    ELIFE, 2019, 8
  • [8] Quaternary ammonium blockade of cyclic nucleotide-gated (CNG) channels
    Contreras, JE
    Holmgren, M
    BIOPHYSICAL JOURNAL, 2005, 88 (01) : 292A - 292A
  • [9] The gating mechanism in cyclic nucleotide-gated ion channels
    Monica Mazzolini
    Manuel Arcangeletti
    Arin Marchesi
    Luisa M. R. Napolitano
    Debora Grosa
    Sourav Maity
    Claudio Anselmi
    Vincent Torre
    Scientific Reports, 8
  • [10] Gating of cyclic nucleotide-gated channels is voltage dependent
    Arin Marchesi
    Monica Mazzolini
    Vincent Torre
    Nature Communications, 3