Using DNA to program the self-assembly of colloidal nanoparticles and microparticles

被引:285
|
作者
Rogers, W. Benjamin [1 ,2 ]
Shih, William M. [3 ,4 ,5 ]
Manoharan, Vinothan N. [1 ,6 ]
机构
[1] Harvard Univ, Harvard John A Paulson Sch Engn & Appl Sci, Cambridge, MA 02138 USA
[2] Brandeis Univ, Martin A Fisher Sch Phys, Waltham, MA 02453 USA
[3] Harvard Univ, Wyss Inst Biol Inspired Engn, Boston, MA 02115 USA
[4] Harvard Univ, Sch Med, Dana Farber Canc Inst, Dept Canc Biol, Boston, MA 02115 USA
[5] Harvard Univ, Sch Med, Dept Biol Chem & Mol Pharmacol, Boston, MA 02115 USA
[6] Harvard Univ, Dept Phys, Cambridge, MA 02138 USA
来源
NATURE REVIEWS MATERIALS | 2016年 / 1卷 / 03期
基金
美国国家科学基金会;
关键词
BLOCK-COPOLYMERS; RATIONAL DESIGN; SHAPE CONTROL; WEB SERVER; CRYSTALLIZATION; NANOSTRUCTURES; TRANSFORMATIONS; NANOTECHNOLOGY; HYBRIDIZATION; SUPERLATTICES;
D O I
10.1038/natrevmats.2016.8
中图分类号
TB3 [工程材料学];
学科分类号
0805 ; 080502 ;
摘要
DNA is not just the stuff of our genetic code; it is also a means to design self-assembling materials. Grafting DNA onto nano-and microparticles can, in principle, 'program' them with information that tells them exactly how to self-assemble. Although fully programmable assembly has not yet been realized, the groundwork has been laid: with an understanding of how specific interparticle attractions arise from DNA hybridization, we can now make systems that reliably assemble in and out of equilibrium. We discuss these advances, and the design rules that will allow us to control - and ultimately program - the assembly of new materials.
引用
收藏
页数:14
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