Antidepressant use in psychiatry and medicine - Importance for dental practice

被引:26
作者
Keene, JJ
Galasko, GT
Land, MF
机构
[1] So Illinois Univ, Sch Dent Med, Dept Appl Dent Med, Pharmacol Sect, Alton, IL 62002 USA
[2] So Illinois Univ, Sch Dent Med, Dept Restorat Dent, Alton, IL USA
关键词
D O I
10.14219/jada.archive.2003.0019
中图分类号
R78 [口腔科学];
学科分类号
1003 ;
摘要
Background. Many dental patients receive antidepressant therapy. However, antidepressants taken with other drugs may increase the risk of complications that require special dental precautions and care. Methods. The authors conducted a retrospective study of 1,800 randomly selected patient records and evaluated the prevalence of using antidepressants and other medications concurrently. They analyzed antidepressant intake relative to drug classification and mechanism of action, age, sex and associated potential for clinical complications cations such as xerostomia, orthostatic hypotension and interaction with vasoconstrictors. The potential for additive adverse effects between antidepressants and other medications also was analyzed. Results. Three hundred eighty-one (21 percent) of the 1,800 patient records indicated that patients were being treated with 412 antidepressants. Female subjects outnumbered male subjects by an approximate 2.3:1 ratio. Selective serotonin reuptake inhibitors were most commonly prescribed, followed by tricyclic antidepressants, atypical and third-generation antidepressants, and monoamine oxidase inhibitors. Based on reported medication intake, almost-58 percent of subjecs in the antidepressant group were receiving treatment with two or more medications that had the potential for dubing xerostomia. Two hundred fiftypercent) of the 381 records documented intake of an antidepressant or other medication with orthostatic hypotension potential. Conclusions. Three hundred eighty-one patients reported that they were receiving antidepressant therapy for psychiatric and other medical reasons. Potential adverse effects and interactions with other medications have direct implications for dental treatment. Clinical implications. Patients receiving antidepressant therapy are at risk of developing xerostomia. and orthostatic hypotension, as well as experiencing the adverse effects of interaction with vasoconstrictors Dentists must take appropriate precautions in treating these patients.
引用
收藏
页码:71 / 79
页数:9
相关论文
共 88 条
  • [51] PEDIATRIC BONE-MARROW TRANSPLANTS - PSYCHOLOGICAL-ASPECTS
    MCCONVILLE, BJ
    STEICHENASCH, P
    HARRIS, R
    NEUDORF, S
    SAMBRANO, J
    LAMPKIN, B
    BAILEY, D
    FREDRICK, B
    HOFFMANN, C
    WOODMAN, D
    [J]. CANADIAN JOURNAL OF PSYCHIATRY-REVUE CANADIENNE DE PSYCHIATRIE, 1990, 35 (09): : 769 - 775
  • [52] Impact of older adults on private dental practices, 1988-1998
    Meskin, L
    Berg, R
    [J]. JOURNAL OF THE AMERICAN DENTAL ASSOCIATION, 2000, 131 (08) : 1188 - 1195
  • [53] DRUG-INDUCED ORTHOSTATIC HYPOTENSION IN OLDER PATIENTS
    METS, TF
    [J]. DRUGS & AGING, 1995, 6 (03) : 219 - 228
  • [54] Secular trends in antidepressant prescribing in the UK, 1975-1998
    Middleton, N
    Gunnell, D
    Whitley, E
    Dorling, D
    Frankel, S
    [J]. JOURNAL OF PUBLIC HEALTH MEDICINE, 2001, 23 (04): : 262 - 267
  • [55] ANTIDEPRESSANT DRUGS IN ANXIETY DISORDERS
    MODIGH, K
    [J]. ACTA PSYCHIATRICA SCANDINAVICA, 1987, 76 : 57 - 71
  • [56] MODY GM, 1990, S AFR MED J, V77, P497
  • [57] Cardiac disorders and antidepressant medications
    Murray, JB
    [J]. JOURNAL OF PSYCHOLOGY, 2000, 134 (02) : 162 - 168
  • [58] Treatment of fibromyalgia with antidepressants - A meta-analysis
    O'Malley, PG
    Balden, E
    Tomkins, G
    Santoro, J
    Kroenke, K
    Jackson, JL
    [J]. JOURNAL OF GENERAL INTERNAL MEDICINE, 2000, 15 (09) : 659 - 666
  • [59] Risks for oral health with the use of antidepressants
    Peeters, FPML
    deVries, MW
    Vissink, A
    [J]. GENERAL HOSPITAL PSYCHIATRY, 1998, 20 (03) : 150 - 154
  • [60] PERRY PJ, 1997, PSYCHOTROPIC DRUG HD, P131