TAHITIAN NONI™ equine Essentials™ regulates LPS-induced COX-2 and cytokine expression in equine neonatal monocytes:: A preliminary study

被引：0

作者：

Xu, J. ^{[1
]}

Cai, J. ^{[1
]}

Godbee, R. G. ^{[2
]}

Peek, S. F. ^{[1
]}

Darien, B. J. ^{[1
]}

机构：

[1] Univ Wisconsin, Sch Vet Med, 2015 Linden Dr, Madison, WI 53706 USA

[2] Univ Nevada, Reno, NV 89557 USA

来源：

NUTRITION AND FEEDING OF THE BROODMARE | 2006年 / 120期

关键词：

TAHITIAN NONI (TM) equine Essentials (TM); foal; COX-2; anti-inflammatory;

D O I：

暂无

中图分类号：

S8 [畜牧、动物医学、狩猎、蚕、蜂];

学科分类号：

0905 ;

摘要：

Morinda citrifolia (NONI) has anti-inflammatory and immune enhancing effects. The objective of this study was to investigate the effects of TAHITIAN NONI (TM) Equine Essentials (TM) on endotoxin induced COX-2 and cytokine expression in equine monocytes from neonates during the first 60 days of life. Peripheral monocytes were collected from 4 foals aged 0, 10 and 60 days. Two foals were fed NONI for 60 days starting at I day after birth. LPS stimulated monocytes from NONI (TM) treated foal had reduced expression of COX-2, TNF-alpha., IL-1 beta, IL-8 and IL-6 compared to untreated controls. These preliminary results suggest that NONI may be a promising nutritional supplement for foals at risk from gram-negative septicaemia.

引用

页码：259 / +

页数：2