Nutraceuticals: Transformation of Conventional Foods into Health Promoters/Disease Preventers and Safety Considerations

被引:100
作者
AlAli, Mudhi [1 ]
Alqubaisy, Maream [1 ]
Aljaafari, Mariam Nasser [1 ]
AlAli, Asma Obaid [1 ]
Baqais, Laila [1 ]
Molouki, Aidin [2 ]
Abushelaibi, Aisha [3 ]
Lai, Kok-Song [1 ]
Lim, Swee-Hua Erin [1 ]
机构
[1] Abu Dhabi Womens Coll, Hlth Sci Div, Higher Coll Technol, Abu Dhabi 41012, U Arab Emirates
[2] Agr Res Educ & Extens Org AREEO, Razi Vaccine & Serum Res Inst, Dept Avian Dis Res & Diagnost, Karaj 31585854, Iran
[3] Dubai Coll, Higher Coll Technol, Dubai 16062, U Arab Emirates
关键词
functional foods; anti-cancer; anti-inflammation; antioxidant activity; anti-lipid activity; nutraceuticals safety and toxicity; RED YEAST RICE; INFLAMMATORY-BOWEL-DISEASE; CURCUMIN INHIBITS PROLIFERATION; FUNCTIONAL FOODS; IN-VITRO; ALOE-VERA; OXIDATIVE STRESS; PYRROLIZIDINE ALKALOIDS; DOUBLE-BLIND; GREEN TEA;
D O I
10.3390/molecules26092540
中图分类号
Q5 [生物化学]; Q7 [分子生物学];
学科分类号
071010 ; 081704 ;
摘要
Nutraceuticals are essential food constituents that provide nutritional benefits as well as medicinal effects. The benefits of these foods are due to the presence of active compounds such as carotenoids, collagen hydrolysate, and dietary fibers. Nutraceuticals have been found to positively affect cardiovascular and immune system health and have a role in infection and cancer prevention. Nutraceuticals can be categorized into different classes based on their nature and mode of action. In this review, different classifications of nutraceuticals and their potential therapeutic activity, such as anti-cancer, antioxidant, anti-inflammatory and anti-lipid activity in disease will be reviewed. Moreover, the different mechanisms of action of these products, applications, and safety upon consumers including current trends and future prospect of nutraceuticals will be included.
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页数:28
相关论文
共 268 条
[1]   Effects of a nutraceutical combination (berberine, red yeast rice and policosanols) on lipid levels and endothelial function randomized, double-blind, placebo-controlled study [J].
Affuso, F. ;
Ruvolo, A. ;
Micillo, F. ;
Sacca, L. ;
Fazio, S. .
NUTRITION METABOLISM AND CARDIOVASCULAR DISEASES, 2010, 20 (09) :656-661
[2]   Toxicity and Protective Effect of Phenolic-Enriched Ethylacetate Fraction of Ocimum gratissimum (Linn.) Leaf against Acute Inflammation and Oxidative Stress in Rats [J].
Ajayi, Abayomi M. ;
Umukoro, Solomon ;
Ben-Azu, Benneth ;
Adzu, Bulus ;
Ademowo, Olusegun G. .
DRUG DEVELOPMENT RESEARCH, 2017, 78 (3-4) :135-145
[3]   Inhibition of PI3K signaling triggered apoptotic potential of curcumin which is hindered by Bcl-2 through activation of autophagy in MCF-7 cells [J].
Akkoc, Yunus ;
Berrak, Ozge ;
Arisan, Elif Damla ;
Obakan, Pinar ;
Coker-Gurkan, Ajda ;
Palavan-Unsal, Narcin .
BIOMEDICINE & PHARMACOTHERAPY, 2015, 71 :161-171
[4]   Antioxidant and antitumor activities of Artemisia campestris and Thymelaea hirsuta from southern Tunisia [J].
Akrout, Ahmed ;
Alarcon Gonzalez, Lidia ;
El Jani, Hajer ;
Campra Madrid, Pablo .
FOOD AND CHEMICAL TOXICOLOGY, 2011, 49 (02) :342-347
[5]   Diets, functional foods, and nutraceuticals as alternative therapies for inflammatory bowel disease: Present status and future trends [J].
Al Mijan, Mohammad ;
Lim, Beong Ou .
WORLD JOURNAL OF GASTROENTEROLOGY, 2018, 24 (25) :2673-2685
[6]   Nutraceuticals of anti-inflammatory activity as complementary therapy for rheumatoid arthritis [J].
Al-Okbi, Sahar Y. .
TOXICOLOGY AND INDUSTRIAL HEALTH, 2014, 30 (08) :738-749
[7]   Prebiotics as functional foods: A review [J].
Al-Sheraji, Sadeq Hasan ;
Ismail, Amin ;
Manap, Mohd Yazid ;
Mustafa, Shuhaimi ;
Yusof, Rokiah Mohd ;
Hassan, Fouad Abdulrahman .
JOURNAL OF FUNCTIONAL FOODS, 2013, 5 (04) :1542-1553
[8]  
Alamgir ANM, 2017, PROG DRUG RES, V73, P1, DOI 10.1007/978-3-319-63862-1
[9]   Gingerol protects against experimental liver fibrosis in rats via suppression of pro-inflammatory and profibrogenic mediators [J].
Algandaby, Mardi M. ;
El-Halawany, Ali M. ;
Abdallah, Hossam M. ;
Alahdal, Abdulrahman M. ;
Nagy, Ayman A. ;
Ashour, Osama M. ;
Abdel-Naim, Ashraf B. .
NAUNYN-SCHMIEDEBERGS ARCHIVES OF PHARMACOLOGY, 2016, 389 (04) :419-428
[10]   Functional Foods and Lifestyle Approaches for Diabetes Prevention and Management [J].
Alkhatib, Ahmad ;
Tsang, Catherine ;
Tiss, Ali ;
Bahorun, Theeshan ;
Arefanian, Hossein ;
Barake, Roula ;
Khadir, Abdelkrim ;
Tuomilehto, Jaakko .
NUTRIENTS, 2017, 9 (12)