Chemical composition and anti-Helicobacter pylori activity of the essential oil of Pistacia vera

被引：16
|
作者：
Ramezani, M
Khaje-Karamoddin, M
Karimi-Fard, V
机构：
[1] Sch Pharm, Mashhad, Iran
[2] Pharmaceut Res Ctr, Dept Pharmacognosy & Biotechnol, Mashhad, Iran
[3] Biotechnol Res Ctr, Dept Pharmacognosy & Biotechnol, Mashhad, Iran
[4] Ghaem Hosp, Sch Med, Dept Med Microbiol, Mashhad, Iran
来源：
PHARMACEUTICAL BIOLOGY | 2004年 / 42卷 / 07期
关键词：
Anti-Helicobacter; essential oils; Helicobacter pylori; pinene; Pistacia vera L; thujene;
D O I：
10.3109/13880200490891755
中图分类号：
Q94 [植物学];
学科分类号：
071001 ;
摘要：
The chemical composition of the essential oil obtained by hydrodistillation of Pistacia vera L. gum was analyzed using Gas Chromatography-Mass Spectrometry (GC-MS). Twenty compounds were identified, representing 99.5% of the total components. alpha-Pinene, beta-pinene, and alpha-thujene were found to be the major constituents. The bacteriostatic activity of the essential oil against 12 clinical isolates of Helicobacter pylori was determined using the hole-plate method. All isolates were sensitive to the essential oil, and the Minimum Inhibition Concentration (MIC) was 1.55 mg/ml for all isolates using the agar dilution method.
引用
收藏
页码：488 / 490
页数：3
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