Highly synergistic interaction between farnesyltransferase inhibitors and the Chk1 inhibitor UCN-01 to induce apoptosis in human leukemia cells through interruption of both Akt and MEK/ERK pathways and activation of SEKI/JNK.

被引：0

作者：

Dai, Y

Rahmani, M

Pei, XY

Khanna, P

Dent, P

Grant, S

机构：

[1] Virginia Commonwealth Univ, Med Coll Virginia, Dept Med, Richmond, VA 23298 USA

[2] Virginia Commonwealth Univ, Med Coll Virginia, Dept Radiat Oncol, Richmond, VA 23298 USA

来源：

关键词：

D O I：

10.1182/blood.V104.11.3403.3403

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

3403

引用

页码：928A / 929A

页数：2