Occurrence of pharmaceuticals and cocaine in a Brazilian coastal zone

被引：173

作者：

Seabra Pereira, Camilo D. ^{[1
,2
]}

Maranho, Luciane A. ^{[1
]}

Cortez, Fernando S. ^{[2
]}

Pusceddu, Fabio H. ^{[2
]}

Santos, Aldo R. ^{[2
]}

Ribeiro, Daniel A. ^{[3
]}

Cesar, Augusto ^{[1
,2
]}

Guimaraes, Luciana L. ^{[4
]}

机构：

[1] Univ Fed Sao Paulo, Dept Ciencias Mar, Ave Saldanha da Gama 89, BR-11030400 Santos, SP, Brazil

[2] Univ Santa Cecilia, Lab Ecotoxicol, Rua Oswaldo Cruz 266, BR-11045907 Santos, SP, Brazil

[3] Univ Fed Sao Paulo, Dept Biociencias, Ave Ana Costa 95, BR-11060001 Santos, SP, Brazil

[4] Univ Santa Cecilia, PPG Sustentabilidade Ecossistemas Costeiros & Mar, Lab Pesquisa Prod Nat, Rua Cesario Mota 8, BR-11045040 Santos, SP, Brazil

来源：

SCIENCE OF THE TOTAL ENVIRONMENT | 2016年 / 548卷

关键词：

Pharmaceuticals; Cocaine; Submarine sewage outfall; Subtropical zone; Marine environment; PERSONAL CARE PRODUCTS; MULTI-RESIDUE ANALYSIS; ILLICIT DRUGS; WASTE-WATER; EMERGING CONTAMINANTS; SPATIAL-DISTRIBUTION; SURFACE WATERS; SANTOS BAY; SEWAGE; METABOLITES;

D O I：

10.1016/j.scitotenv.2016.01.051

中图分类号：

X [环境科学、安全科学];

学科分类号：

08 ; 0830 ;

摘要：

The present study determined environmental concentrations of pharmaceuticals, cocaine, and the main human metabolite of cocaine in seawater sampled from a subtropical coastal zone (Santos, Brazil). The Santos Bay is located in a metropolitan region and receives over 7367 m(3) of wastewater per day. Five sample points under strong influence of the submarine sewage outfall were chosen. Through quantitative analysis by LC-MS/MS, 33 compounds were investigated. Seven pharmaceuticals (atenolol, acetaminophen, caffeine, losartan, valsartan, diclofenac, and ibuprofen), an illicit drug (cocaine), and its main humanmetabolite (benzoylecgonine) were detected at least once in seawater sampled from Santos Bay at concentrations that ranged from ng.L-1 to mu g.L-1. In light of the possibility of bioaccumulation and harmful effects, the high concentrations of pharmaceuticals and cocaine found in this marine subtropical ecosystem are of environmental concern. (C) 2016 Elsevier B.V. All rights reserved.

引用

页码：148 / 154

页数：7

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