Functionalized polyester-based materials as UV curable adhesives

被引：19

作者：

Cernadas, T. ^{[1
]}

Santos, M. ^{[1
]}

Goncalves, F. A. M. M. ^{[1
]}

Alves, P. ^{[1
]}

Correia, T. R. ^{[2
]}

Correia, I. J. ^{[1
,2
]}

Ferreira, P. ^{[1
]}

机构：

[1] Univ Coimbra, Dept Chem Engn, CIEPQPF, P-3030790 Coimbra, Portugal

[2] UBI, Hlth Sci Res Ctr, CICS, P-6200506 Covilha, Portugal

来源：

EUROPEAN POLYMER JOURNAL | 2019年 / 120卷

关键词：

Photocrosslinking; Polyesters; Bioadhesive; UV curing; HYDROGELS; CHITOSAN; HEMOCOMPATIBILITY; THROMBOGENICITY; POLYMERIZATION; BIOMATERIALS; BIOADHESIVE;

D O I：

10.1016/j.eurpolymj.2019.08.023

中图分类号：

O63 [高分子化学（高聚物）];

学科分类号：

070305 ; 080501 ; 081704 ;

摘要：

UV curable adhesives offer major advantages in comparison to other polymeric based adhesive systems, such as fast-curing rate and control of the polymerization heat evolution, being ideal for application on damaged tissues. Herein, functionalized polymers were prepared by modifying polycaprolactone diol (PCL) with an isocyanate-functional unsaturated acrylic ester, Laromer (R) 9000, using two different proportions. These functionalized materials were chemically/physically characterized and, after the addition of a biocompatible photoinitiator (Irgacure (R) 2959), were crosslinked by UV light irradiation. Such procedure allows the obtention of flexible transparent films. Films' properties such as swelling, hydrolytic degradation, thermal stability, surface energy and adhesive capacity were evaluated. Furthermore, to assess the applicability of the films in biomedical applications, their haemocompatibility and biocompatibility were determined using human dermal fibroblasts as model.

引用

页数：10

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