Intravenous Vitamin C Administration Improved Blood Cell Counts and Health-Related Quality of Life of Patient with History of Relapsed Acute Myeloid Leukaemia

被引:14
作者
Foster, Mike N. [1 ]
Carr, Anitra C. [2 ]
Antony, Alina [3 ]
Peng, Selene [3 ]
Fitzpatrick, Mike G. [3 ]
机构
[1] Integrated Hlth Opt Ltd, Auckland 1050, New Zealand
[2] Univ Otago, Dept Pathol & Biomed Sci, Christchurch 8011, New Zealand
[3] Feedback Res Ltd, Auckland 1050, New Zealand
关键词
vitamin C; intravenous vitamin C; leukemia; acute myeloid leukemia; AML; ASCORBATE; TET2;
D O I
10.3390/antiox7070092
中图分类号
Q5 [生物化学]; Q7 [分子生物学];
学科分类号
071010 ; 081704 ;
摘要
A 52-year-old female presented to Integrated Health Options Clinic in October 2014 with a history of relapsed acute myeloid leukaemia (AML, diagnosed in 2009 and relapsed in 2014). Intravenous(IV) vitamin C therapy was initiated (in 2014) following completion of chemotherapy as an alternative to haematopoietic stem cell transplantation. IV vitamin C was administered twice weekly at a dose of 70 g/infusion. Within 4 weeks of initiation of IV vitamin C therapy, there was a dramatic improvement in the patient's blood indices with platelet cell counts increasing from 25 x 10(9)/L to 196 x 10(9)/L and white blood cell counts increasing from 0.29 x 10(9)/L to 4.0 x 10(9)/L, with further improvements observed over the next 18 months. Furthermore, there was a clear and sustained improvement in the patient's health-related quality of life scores assessed using a validated questionnaire. She has remained healthy and in complete remission until the present day. This case study highlights the benefits of IV vitamin C as a supportive therapy for previously relapsed AML.
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页数:7
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