Management of Chlorine Gas-Related Injuries From the Graniteville, South Carolina, Train Derailment

被引：35
作者：
Mackie, Emily [1 ]
Svendsen, Erik [3 ]
Grant, Stephen [4 ]
Michels, Jill E. [2 ]
Richardson, William H. [1 ,2 ]
机构：
[1] Palmetto Hlth Richland, Dept Emergency Med, Columbia, SC 29203 USA
[2] Univ S Carolina, Palmetto Poison Ctr, South Carolina Coll Pharm, Columbia, SC 29208 USA
[3] Tulane Univ, Sch Publ Hlth & Trop Med, Dept Global Environm Hlth Sci, New Orleans, LA USA
[4] North Fulton Hosp, Dept Emergency Med, Roswell, GA USA
来源：
DISASTER MEDICINE AND PUBLIC HEALTH PREPAREDNESS | 2014年 / 8卷 / 05期
关键词：
chlorine; inhalation; train; disaster; NEBULIZED SODIUM-BICARBONATE; AIRWAY HYPERRESPONSIVENESS; ACUTE INHALATION; MASS CASUALTIES; LUNG; EXPOSURE; INFLAMMATION; CORTICOSTEROIDS; TOXICOLOGY;
D O I：
10.1017/dmp.2014.81
中图分类号：
R1 [预防医学、卫生学];
学科分类号：
1004 ; 120402 ;
摘要：
A widely produced chemical, chlorine is used in various industries including automotive, electronics, disinfectants, metal production, and many others. Chlorine is usually produced and transported as a pressurized liquid; however, as a gas it is a significant pulmonary irritant. Thousands of people are exposed to chlorine gas every year, and while large-scale exposures are uncommon, they are not rare. Symptoms are usually related to the concentration and length of exposure, and although treatment is largely supportive, certain specific therapies have yet to be validated with randomized controlled trials. The majority of those exposed completely recover with supportive care; however, studies have shown the potential for persistent inflammation and chronic hyperreactivity. This case report describes an incident that occurred in Graniteville, South Carolina, when a train derailment exposed hundreds of people to chlorine gas. This report reviews the events of January 6, 2005, and the current treatment options for chlorine gas exposure.
引用
收藏
页码：411 / 416
页数：6
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