A microsatellite genetic linkage map for zebrafish (Danio rerio)

被引：283

作者：

Knapik, EW

Goodman, A

Ekker, M

Chevrette, M

Delgado, J

Neuhauss, S

Shimoda, N

Driever, W

Fishman, MC

Jacob, HJ

机构：

[1] Massachusetts Gen Hosp, Cardiovasc Res Ctr, Charlestown, MA 02129 USA

[2] Univ Ottawa, Ottawa Civic Hosp, Loeb Inst Med Res, Ottawa, ON K1Y 4E9, Canada

[3] McGill Univ, Dept Surg, Montreal, PQ H3G 1A4, Canada

[4] Montreal Gen Hosp, Res Inst, Montreal, PQ H3G 1A4, Canada

来源：

NATURE GENETICS | 1998年 / 18卷 / 04期

关键词：

D O I：

10.1038/ng0498-338

中图分类号：

Q3 [遗传学];

学科分类号：

071007 ; 090102 ;

摘要：

We have constructed a zebrafish genetic linkage map consisting of 705 simple sequence-length polymorphism markers (SSLPs). The map covers 2350 centimorgans (cM) of the zebrafish genome with an average resolution of 3.3 cM. It is a complete map in genetic mapping terms (there is one linkage group for each of the 25 chromosomes), and it has been confirmed by somatic-cell hybrids and centromere-mapping using half-tetrad analysis. The markers are highly polymorphic in the zebrafish strains used for genetic crosses and provide a means to compare genetic segregation of developmental mutations between laboratories. These markers will provide an initial infrastructure for the positional cloning of the nearly 600 zebrafish genes identified as crucial to vertebrate development,and will become the anchor for the physical map of the zebrafish genome.

引用

页码：338 / 343

页数：6

共 33 条

[1]

BISHOP MD, 1994, GENETICS, V136, P619

[2] TOWARDS HIGH-RESOLUTION MAPS OF THE MOUSE AND HUMAN GENOMES - A FACILITY FOR ORDERING MARKERS TO 0.1 CM RESOLUTION [J].

BREEN, M ;

DEAKIN, L ;

MACDONALD, B ;

MILLER, S ;

SIBSON, R ;

TARTTELIN, E ;

AVNER, P ;

BOURGADE, F ;

GUENET, JL ;

MONTAGUTELLI, X ;

POIRIER, C ;

SIMON, D ;

TAILOR, D ;

BISHOP, M ;

KELLY, M ;

RYSAVY, F ;

RASTAN, S ;

NORRIS, D ;

SHEPHERD, D ;

ABBOTT, C ;

PILZ, A ;

HODGE, S ;

JACKSON, I ;

BOYD, Y ;

BLAIR, H ;

MASLEN, G ;

TODD, JA ;

REED, PW ;

STOYE, J ;

ASHWORTH, A ;

MCCARTHY, L ;

COX, R ;

SCHALKWYK, L ;

LEHRACH, H ;

KLOSE, J ;

GANGADHARAN, U ;

BROWN, S .

HUMAN MOLECULAR GENETICS, 1994, 3 (04) :621-627

[3]

CHIN AJ, 1997, DEV GENES EVOL, V207, P104

[4] GENOMIC SEQUENCING [J].

CHURCH, GM ;

GILBERT, W .

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA-BIOLOGICAL SCIENCES, 1984, 81 (07) :1991-1995

[5] A metric map of humans: 23,500 loci in 850 bands [J].

Collins, A ;

Frezal, J ;

Teague, J ;

Morton, NE .

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 1996, 93 (25) :14771-14775

[6]

CRAWFORD AM, 1995, GENETICS, V140, P703

[7] Chromosome complement, C-banding, Ag-NOR and replication banding in the zebrafish Danio rerio [J].

Daga, RR ;

Thode, G ;

Amores, A .

CHROMOSOME RESEARCH, 1996, 4 (01) :29-32

[8] A comprehensive genetic map of the human genome based on 5,264 microsatellites [J].

Dib, C ;

Faure, S ;

Fizames, C ;

Samson, D ;

Drouot, N ;

Vignal, A ;

Millasseau, P ;

Marc, S ;

Hazan, J ;

Seboun, E ;

Lathrop, M ;

Gyapay, G ;

Morissette, J ;

Weissenbach, J .

NATURE, 1996, 380 (6570) :152-154

[9] A GENETIC-MAP OF THE MOUSE WITH 4,006 SIMPLE SEQUENCE LENGTH POLYMORPHISMS [J].

DIETRICH, WF ;

MILLER, JC ;

STEEN, RG ;

MERCHANT, M ;

DAMRON, D ;

NAHF, R ;

GROSS, A ;

JOYCE, DC ;

WESSEL, M ;

DREDGE, RD ;

MARQUIS, A ;

STEIN, LD ;

GOODMAN, N ;

PAGE, DC ;

LANDER, ES .

NATURE GENETICS, 1994, 7 (02) :220-245

[10] A comprehensive genetic map of the mouse genome [J].

Dietrich, WF ;

Miller, J ;

Steen, R ;

Merchant, MA ;

DamronBoles, D ;

Husain, Z ;

Dredge, R ;

Daly, MJ ;

Ingalls, KA ;

OConnor, TJ ;

Evans, CA ;

DeAngelis, MM ;

Levinson, DM ;

Kruglyak, L ;

Goodman, N ;

Copeland, NG ;

Jenkins, NA ;

Hawkins, TL ;

Stein, L ;

Page, DC ;

Lander, ES .

NATURE, 1996, 380 (6570) :149-152

← 1 2 3 4 →