H pylori are associated with chronic cholecystitis

被引：12

作者：

Chen, Dong-Feng ^{[1
]}

Hu, Lu ^{[1
]}

Yi, Ping ^{[1
]}

Liu, Wei-Wen ^{[1
]}

Fang, Dian-Chun ^{[1
]}

Cao, Hong ^{[1
]}

机构：

[1] Third Mil Med Univ, Daping Hosp, Inst Surg Res, Dept Gastroenterol, Chongqing 400042, Peoples R China

来源：

WORLD JOURNAL OF GASTROENTEROLOGY | 2007年 / 13卷 / 07期

关键词：

H pylori; chronic cholecystitis; interleukin; colonization; gallbladder mucosa;

D O I：

10.3748/wjg.v13.i7.1119

中图分类号：

R57 [消化系及腹部疾病];

学科分类号：

摘要：

AIM: To study whether H pylori are associated with chronic cholecystitis. METHODS: The subjects were divided into three groups: H pylori-infected cholecystitis group, H pylori-negative cholecystitis group and control group. Pathologic changes of the gallbladder were observed by optic and electronic microscopes and the levels of interleukin-1, 6 and 8 (IL-1, 6 and 8) were detected by radioimmunoassay. RESULTS: Histological evidence of chronic cholecystitis including degeneration, necrosis, inflammatory cell infiltration, were found in the region where H pylori colonized. Levels of IL-1, 6 and 8 in gallbladder mucosa homogenates were significantly higher in H pylori-infected cholecystitis group than those in H pylori-negative cholecystitis group and control group. CONCLUSION: H pylori infection may be related to cholecystitis. (c) 2007 The WJG Press. All rights reserved.

引用

页码：1119 / 1122

页数：4

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