Benign and malignant hybrid adnexal tumors in a patient with epidermodysplasia verruciformis

被引:3
作者
Ho, Jonathan D. [1 ,2 ]
Kam, Sarah A. [1 ]
Al-Haseni, Ali [1 ]
Markova, Alina [1 ]
Sahni, Debjani [1 ]
Lam, Christina [1 ]
Goldberg, Lynne J. [1 ,2 ]
Bhawan, Jag [1 ,2 ]
机构
[1] Boston Univ, Sch Med, Dept Dermatol, 609 Albany St, Boston, MA 02118 USA
[2] Boston Univ, Dept Pathol & Lab Med, 609 Albany St, Boston, MA 02118 USA
关键词
cutaneous adnexal neoplasm; epidermodysplasia verruciformis; HPV-induced tumors; HUMAN-PAPILLOMAVIRUS; INFECTION; DISEASE; SKIN;
D O I
10.1111/cup.13022
中图分类号
R75 [皮肤病学与性病学];
学科分类号
100206 ;
摘要
Epidermodysplasia verruciformis (EV) is a genodermatosis characterized by overgrowth of flat warts, pityriasis versicolor-like lesions and an increased propensity for developing cutaneous squamous cell carcinomas due to abnormal susceptibility to infection with beta-human papilloma viruses. Adnexal tumors are not typically associated with EV. Here we report a spectrum of hybrid adnexal tumors with divergent eccrine and folliculosebaceous differentiation, and cytologic features ranging from benign to frankly atypical, in a patient with inherited EV.
引用
收藏
页码:969 / 973
页数:5
相关论文
共 11 条
[1]   Epidermodysplasia verruciformis: An unusual malignant transformation [J].
Agrawal, Prachi G. ;
Mahajan, Sunanda A. ;
Khopkar, Uday S. ;
Kharkar, Vidya D. .
INDIAN JOURNAL OF DERMATOLOGY VENEREOLOGY & LEPROLOGY, 2013, 79 (01) :97-99
[2]   X-LINKED INHERITANCE OF EPIDERMODYSPLASIA VERRUCIFORMIS - GENETIC AND VIROLOGIC STUDIES OF A KINDRED [J].
ANDROPHY, EJ ;
DVORETZKY, I ;
LOWY, DR .
ARCHIVES OF DERMATOLOGY, 1985, 121 (07) :864-868
[3]   A novel homozygous mutation of the EVER1/TMC6 gene in a Japanese patient with epidermodysplasia verruciformis [J].
Aochi, S. ;
Nakanishi, G. ;
Suzuki, N. ;
Setsu, N. ;
Suzuki, D. ;
Aya, K. ;
Iwatsuki, K. .
BRITISH JOURNAL OF DERMATOLOGY, 2007, 157 (06) :1265-1266
[4]  
GALADARI I, 1993, CUTIS, V52, P53
[5]   Reactive syringofibroadenomatous hyperplasia in peristomal skin with formation of hybrid epidermal-colonic mucosa glandular structures, intraepidermal areas of sebaceous differentiation, induction of hair follicles, and features of human papillomavirus infection - A diagnostic pitfall [J].
Kazakov, DV ;
Mikyskova, I ;
Mukensnabl, P ;
Brouckova, M ;
Treska, V ;
Hes, O ;
Michal, M .
AMERICAN JOURNAL OF DERMATOPATHOLOGY, 2005, 27 (02) :135-141
[6]   A Coding Variant in TMC8 (EVER2) Is Associated with High Risk HPV Infection and Head and Neck Cancer Risk [J].
Liang, Caihua ;
Kelsey, Karl T. ;
McClean, Michael D. ;
Christensen, Brock C. ;
Marsit, Carmen J. ;
Karagas, Margaret R. ;
Waterboer, Tim ;
Pawlita, Michael ;
Nelson, Heather H. .
PLOS ONE, 2015, 10 (04)
[7]  
LUTZNER MA, 1978, B CANCER, V65, P169
[8]   Epidermodysplasia verruciformis with keratoacanthoma, Bowen's disease and squamous cell carcinoma: isolation of high-risk types of HPV 5 and unknown type of human papillomavirus [J].
Mitsuishi, T. ;
Ohara, K. ;
Suzuki, T. ;
Mochizuki, T. ;
Kaneko, T. ;
Kawana, S. .
JOURNAL OF THE EUROPEAN ACADEMY OF DERMATOLOGY AND VENEREOLOGY, 2008, 22 (09) :1126-1127
[9]   Genetics of epidermodysplasia verruciformis: Insights into host defense against papillomaviruses [J].
Orth, Gerard .
SEMINARS IN IMMUNOLOGY, 2006, 18 (06) :362-374
[10]  
Sanclemente G, 2007, INT J DERMATOL, V46, P199