Off-label application of intravenous immunoglobulin (IVIG) for treatment of Cogan's syndrome during pregnancy

被引：3

作者：

Scherg, Felix ^{[1
]}

Haag, Friedrich ^{[1
]}

Krieger, Thorsten ^{[2
,3
]}

机构：

[1] Univ Med Ctr Hamburg Eppendorf, Inst Immunol, Hamburg, Germany

[2] Univ Med Ctr Hamburg Eppendorf, Inst Clin Chem, Hamburg, Germany

[3] MVZ Rheumatol & Autoimmunmed GmbH, Dept Primary Immunodeficiencies, Hamburg, Germany

来源：

BMJ CASE REPORTS | 2019年 / 12卷 / 10期

关键词：

immunology; pregnancy; ear; nose And throat; INNER-EAR; PREECLAMPSIA; AUTOIMMUNE; FAILURE; MARKERS;

D O I：

10.1136/bcr-2018-227917

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

We report the case of a woman with Cogan's syndrome concomitant with the wish to have children. After three major flares of the disease that led to unilateral deafness, immunosuppressive therapy with prednisolone and azathioprine was started. Because of the severe side effects, an off-label therapy with intravenous immunoglobulin (IVIG) was initiated, under which our patient has since given birth to three healthy children. To our knowledge this is the first report to describe Cogan's syndrome with multiple successful pregnancies under IVIG treatment.

引用

页数：4

共 21 条

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