[1] Royal Liverpool Univ Hosp, Intens Care Unit, Liverpool, Merseyside, England
[2] Queens Univ Belfast, Sch Med Dent & Biomed Sci, Belfast, Antrim, North Ireland
[3] Imperial Coll London, Fac Med, Dept Surg & Canc, Sect Anaesthet Pain Med & Intens Care, London, England
[4] Univ Liverpool, Inst Ageing & Chronic Dis, Liverpool, Merseyside, England