5-Butylamino-2-[ 2-(dimethylamino)ethyl]-1H-benz[de]isoquinoline-1,3(2H)-dione

被引：1
|
作者：
Xie, Li-Juan [1 ,2 ]
机构：
[1] Huaqiao Univ, Inst Mol Med, Quanzhou 362021, Fujian, Peoples R China
[2] State Key Lab Oncol S China, Guangzhou 510060, Guangdong, Peoples R China
来源：
ACTA CRYSTALLOGRAPHICA SECTION E-STRUCTURE REPORTS ONLINE | 2010年 / 66卷
关键词：
ACETYLATOR PHENOTYPE;
D O I：
10.1107/S1600536810018702
中图分类号：
O7 [晶体学];
学科分类号：
0702 ; 070205 ; 0703 ; 080501 ;
摘要：
The title compound, C(20)H(25)N(3)O(2), is a new amonafide analogue, which exhibits antitumor activity. The asymmetric unit contains two molecules with similar conformations for the substituted aliphatic chains. The two independent molecules form dmers through N-H center dot center dot center dot N hydrogen bonds. The crystal structure is stabilized via pi-pi stacking interactions, the shortest centroid-centroid separation between six-membered rings being 3.673 (2) angstrom.
引用
收藏
页码：O1454 / U1788
页数：14
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