Visceral adiposity index as a predictor of clinical severity and therapeutic outcome of PCOS

被引：50

作者：

Zheng, Sai-Hua ^{[1
]}

Li, Xue-Lian ^{[1
]}

机构：

[1] Fudan Univ, Shanghai OB GYN Hosp, Shanghai Med Coll, Dept Gynecol,Shanghai Key Lab Female Reprod Endoc, Shanghai 200011, Peoples R China

来源：

GYNECOLOGICAL ENDOCRINOLOGY | 2016年 / 32卷 / 03期

关键词：

Adipose tissue dysfunction; visceral adiposity index; polycystic ovary syndrome; insulin resistance; visceral obesity; POLYCYSTIC-OVARY-SYNDROME; INSULIN-RESISTANCE; CARDIOVASCULAR RISK; BODY-FAT; METABOLIC SYNDROME; GLUCOSE-TOLERANCE; LIVER HISTOLOGY; WOMEN; OBESITY; TISSUE;

D O I：

10.3109/09513590.2015.1111327

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

Polycystic ovary syndrome (PCOS) is a common endocrine-metabolic disease which often accompany with abnormal fat distribution. Visceral adiposity has association with abnormal lipid metabolic, pro-inflammatory activity, insulin resistance (IR) and hyperandrogenism. Increased visceral adiposity raises the risk of metabolic syndrome, type 2 diabetes and cardiovascular (CV) events, and aggravates ovulatory dysfunction and hyperandrogenism in PCOS women. Visceral adiposity index (VAI), a simple surrogate maker of visceral adipose dysfunction and visceral adiposity, is a predictor of IR, and link hyperinsulinemia, hyperandrogenism and anovulation. This review aims to discuss the visceral adiposity situation in PCOS women, and suggests that VAI may be a useful predictor of clinical severity and therapeutic outcome of PCOS.

引用

页码：177 / 183

页数：7

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