Secretory immune response to membrane antigens during Giardia lamblia infection in humans

被引：13
作者：
Rosales-Borjas, DM
Díaz-Rivadeneyra, J
Doña-Leyva, A
Zambrano-Villa, SA
Mascaró, C
Osuna, A
Ortiz-Ortiz, L
机构：
[1] Natl Autonomous Univ Mexico, Inst Invest Biomed, Dept Immunol, Mexico City 04510, DF, Mexico
[2] Univ Granada, Inst Biotecnol, Grp Bioquim & Parasitol Mol, Granada, Spain
[3] EMASAGRA, Granada, Spain
[4] Hosp Univ Dr Miguel Oraa, Guanare, Edo Portuguesa, Venezuela
[5] Univ Guadalajara, Ctr Univ Ciencias Exactas & Ingn, Guadalajara 44430, Jalisco, Mexico
来源：
INFECTION AND IMMUNITY | 1998年 / 66卷 / 02期
关键词：
D O I：
10.1128/IAI.66.2.756-759.1998
中图分类号：
R392 [医学免疫学]; Q939.91 [免疫学];
学科分类号：
100102 ;
摘要：
The secretory immune response in humans infected with Giardia lamblia was studied by using saliva samples and a membrane rich protein fraction, The membrane fraction, studied by sodium dodecyl sulfate-polyacrylamide gel electrophoresis, showed 24 antigen bands, ranging from 170 to 14 kDa, Saliva samples from giardiasis patients showed a heterogeneous response against the membrane fraction when they were assayed by immunoblotting. Among the antigens recognized by patient saliva samples, those of 170, 105, 92, 66, 32, 29, and 14 kDa stood out, These antigens were not recognized by saliva samples from healthy individuals, They may be of importance in future studies of protection from or diagnosis of G, lamblia infections.
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页码：756 / 759
页数：4
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