Unsaturated C3,5,7,9-Monocarboxylic Acids by Aqueous, One-Pot Carbon Fixation: Possible Relevance for the Origin of Life

被引：22

作者：

Scheidler, Christopher ^{[1
]}

Sobotta, Jessica ^{[1
]}

Eisenreich, Wolfgang ^{[1
]}

Waechtershaeuser, Guenter ^{[2
]}

Huber, Claudia ^{[1
]}

机构：

[1] Tech Univ Munich, Lehrstuhl Biochem, Lichtenbergstr 4, D-85747 Garching, Germany

[2] 22209 Mill Race Dr, Chapel Hill, NC 27514 USA

来源：

SCIENTIFIC REPORTS | 2016年 / 6卷

关键词：

MONOCARBOXYLIC ACIDS; ORGANIC-COMPOUNDS; IRON SULFIDE; ACETYLENE; EVOLUTION; PROTEIN; RNA;

D O I：

10.1038/srep27595

中图分类号：

O [数理科学和化学]; P [天文学、地球科学]; Q [生物科学]; N [自然科学总论];

学科分类号：

07 ; 0710 ; 09 ;

摘要：

All scientific approaches to the origin of life share a common problem: a chemical path to lipids as main constituents of extant cellular enclosures. Here we show by isotope-controlled experiments that unsaturated C-3,C-5,C-7,C-9-monocarboxylic acids form by one-pot reaction of acetylene (C2H2) and carbon monoxide (CO) in contact with nickel sulfide (NiS) in hot aqueous medium. The primary products are toto-olefinic monocarboxylic acids with CO-derived COOH groups undergoing subsequent stepwise hydrogenation with CO as reductant. In the resulting unsaturated monocarboxylic acids the double bonds are mainly centrally located with mainly trans-configuration. The reaction conditions are compatible with an origin of life in volcanic-hydrothermal sub-seafloor flow ducts.

引用

页数：7

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