Management of acute spinal cord compression in multiple myeloma

被引:9
作者
Chen, Bo [1 ]
Cai, Lin [2 ]
Zhou, Fuling [1 ]
机构
[1] Wuhan Univ, Zhongnan Hosp, Dept Hematol, 169 Donghu Rd, Wuhan 430071, Hubei, Peoples R China
[2] Wuhan Univ, Dept Orthoped, Zhongnan Hosp, Wuhan 430071, Hubei, Peoples R China
关键词
Multiple myeloma; Spinal cord compression; Anti-plasma cell therapies; Radiation therapy; Surgery; POSITRON-EMISSION-TOMOGRAPHY; BONE-DISEASE; RADIATION-THERAPY; METASTATIC TUMOR; ZOLEDRONIC ACID; DIAGNOSIS; EXTRAMEDULLARY; DEXAMETHASONE; KYPHOPLASTY; BORTEZOMIB;
D O I
10.1016/j.critrevonc.2020.103205
中图分类号
R73 [肿瘤学];
学科分类号
100214 ;
摘要
Spinal cord compression (SCC) is a devastating complication of multiple myeloma and has the potential to cause loss of neurological function. The common symptoms of SCC are back pain, motor weakness, and sensory change. Once diagnosed, the patient should be managed as soon as possible to prevent permanent loss of neurological function. Currently, there have been a number of studies describing the mechanism and management experience of SCC in patients with myeloma. The clinical features, diagnostic strategies, and the roles of different therapeutic options are herein reviewed.
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页数:7
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