Mannan-binding lectin polymorphisms and serum levels in patients with endometriosis

被引:4
|
作者
Kruse, Christina [1 ]
Steffensen, Rudi [2 ]
Nielsen, Hans J. [3 ]
Jensenius, Jens C. [4 ]
机构
[1] Aarhus Univ Hosp, Dept Obstet & Gynaecol, DK-8000 Aarhus, Denmark
[2] Aarhus Univ Hosp, Dept Clin Immunol, DK-8000 Aarhus, Denmark
[3] Hvidovre Univ Hosp, Dept Surg Gastroenterol, DK-2650 Hvidovre, Denmark
[4] Aarhus Univ, Dept Biomed, Aarhus, Denmark
关键词
Endometriosis; Mannan-binding lectin; Immunology; SINGLE-NUCLEOTIDE POLYMORPHISMS; COMPLEMENT COMPONENT 3; AUTOIMMUNE-DISEASE; PERITONEAL-FLUID; EXPRESSION; WOMEN; GENE; MBL; SUSCEPTIBILITY; ASSOCIATION;
D O I
10.1016/j.ejogrb.2014.08.012
中图分类号
R71 [妇产科学];
学科分类号
100211 ;
摘要
Objective: To investigate a possible association between endometriosis and low levels of mannan-binding lectin (MBL). Study design: Case-control study of blood samples from 100 patients with endometriosis compared with results from a group of 350 blood donors. Result: The frequency of MBL levels <100 ng/ml was 14.0% in patients and 14.9% in controls. Correspondingly, the frequencies of low producing MBL genotypes were 15.0% and 16.0%, respectively. Conclusion: No association was found between endometriosis and low levels of MBL. (C) 2014 Elsevier Ireland Ltd. All rights reserved.
引用
收藏
页码:256 / 258
页数:3
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