The efficiency of programmed ribosomal frameshifting in decoding antizyme mRNA is the sensor for an autoregulatory circuit that controls cellular polyamine levels in organisms ranging from the yeast Schizosaccharomyces pombe to Drosophila to mammals. Comparison of the frameshift sites and flanking stimulatory signals in many organisms now permits a reconstruction of the likely evolutionary path of the remarkably conserved mRNA sequences involved in the frameshifting.
机构:
Univ Utah, Dept Biochem, Howard Hughes Med Inst, Salt Lake City, UT 84132 USAUniv Utah, Dept Biochem, Howard Hughes Med Inst, Salt Lake City, UT 84132 USA
Aruscavage, PJ
Bass, BL
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Univ Utah, Dept Biochem, Howard Hughes Med Inst, Salt Lake City, UT 84132 USAUniv Utah, Dept Biochem, Howard Hughes Med Inst, Salt Lake City, UT 84132 USA
机构:
PENN STATE UNIV,MILTON S HERSHEY MED CTR,COLL MED,DEPT CELLULAR & MOL PHYSIOL,HERSHEY,PA 17033PENN STATE UNIV,MILTON S HERSHEY MED CTR,COLL MED,DEPT CELLULAR & MOL PHYSIOL,HERSHEY,PA 17033
Coleman, CS
Pegg, AE
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PENN STATE UNIV,MILTON S HERSHEY MED CTR,COLL MED,DEPT CELLULAR & MOL PHYSIOL,HERSHEY,PA 17033PENN STATE UNIV,MILTON S HERSHEY MED CTR,COLL MED,DEPT CELLULAR & MOL PHYSIOL,HERSHEY,PA 17033
机构:
Univ Utah, Dept Biochem, Howard Hughes Med Inst, Salt Lake City, UT 84132 USAUniv Utah, Dept Biochem, Howard Hughes Med Inst, Salt Lake City, UT 84132 USA
Aruscavage, PJ
Bass, BL
论文数: 0引用数: 0
h-index: 0
机构:
Univ Utah, Dept Biochem, Howard Hughes Med Inst, Salt Lake City, UT 84132 USAUniv Utah, Dept Biochem, Howard Hughes Med Inst, Salt Lake City, UT 84132 USA
机构:
PENN STATE UNIV,MILTON S HERSHEY MED CTR,COLL MED,DEPT CELLULAR & MOL PHYSIOL,HERSHEY,PA 17033PENN STATE UNIV,MILTON S HERSHEY MED CTR,COLL MED,DEPT CELLULAR & MOL PHYSIOL,HERSHEY,PA 17033
Coleman, CS
Pegg, AE
论文数: 0引用数: 0
h-index: 0
机构:
PENN STATE UNIV,MILTON S HERSHEY MED CTR,COLL MED,DEPT CELLULAR & MOL PHYSIOL,HERSHEY,PA 17033PENN STATE UNIV,MILTON S HERSHEY MED CTR,COLL MED,DEPT CELLULAR & MOL PHYSIOL,HERSHEY,PA 17033