C2-symmetric bissulfoximines as ligands in copper-catalyzed enantioselective Diels-Alder reactions

被引：78

作者：

Bolm, C ^{[1
]}

Martin, M ^{[1
]}

Simic, O ^{[1
]}

Verrucci, M ^{[1
]}

机构：

[1] Rhein Westfal TH Aachen, Inst Organ Chem, D-52056 Aachen, Germany

来源：

ORGANIC LETTERS | 2003年 / 5卷 / 04期

关键词：

D O I：

10.1021/ol027273e

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

[GRAPHICS] Bissulfoximines have been used as chiral ligands in copper-catalyzed enantioselective Diels-Alder reactions between acryloyl-2-oxazolidinones and cyclopentadiene. After optimizing the ligand structure, the metal source, the counterions, and the solvent, products with up to 93% ee have been obtained.

引用

页码：427 / 429

页数：3