Effect of Sr on the microstructure and biodegradable behavior of Mg-Zn-Ca-Mn alloys for implant application

被引：64
作者：
Wang, Jingfeng [1 ,2 ]
Ma, Yao [1 ]
Guo, Shengfeng [3 ]
Jiang, Weiyan [1 ]
Liu, Qingshan [1 ]
机构：
[1] Chongqing Univ, Coll Mat Sci & Engn, Natl Engn Res Ctr Magnesium Alloys, Chongqing 400044, Peoples R China
[2] Chongqing Univ, State Key Lab Mech Transmiss, Chongqing 400044, Peoples R China
[3] Southwest Univ, Fac Mat & Energy, Chongqing 400715, Peoples R China
来源：
MATERIALS & DESIGN | 2018年 / 153卷
关键词：
Mg-based amorphous matrix composite; Biodegradable behavior; Biocompatibility; Hydroxyapatite; BULK METALLIC-GLASS; MECHANICAL-PROPERTIES; CORROSION PROPERTIES; FORMING ABILITY; MAGNESIUM;
D O I：
10.1016/j.matdes.2018.04.062
中图分类号：
T [工业技术];
学科分类号：
08 ;
摘要：
In this paper, the effect of Sr on the microstructure and bio-corrosion behavior of Mg65.2-xZn30Ca4Mn0.8Srx (x= 0, 0.3, 0.5 and 0.8) amorphous matrix composite were investigated by X-ray diffraction, differential scanning calorimetry, scanning electron microscope, electrochemical measurements, immersion test and in vitro cytotoxicity test, respectively. Compared to the Mg-Zn-Ca-Mn alloy, the Sr-bearing alloys with minor Sr incorporation improved the glass formation ability and bio-corrosion resistance significantly. The corrosion products of the Mg65.2-xZn30Ca4Mn0.8Srx (x= 0, 0.3, 0.5 and 0.8) alloys mainly contained Zn(OH)(2), hydroxyapatite and phosphate after 124 h static immersion test, which were beneficial to the bone growth. The results suggested that the novel Mg64.7Zn30Ca4Mn0.8Sr0.5 alloy possessed a good corrosion resistance and biocompatibility, showing a promising candidate for the biodegradable implants. (C) 2018 Elsevier Ltd. All rights reserved.
引用
收藏
页码：308 / 316
页数：9
相关论文
共 29 条
[1]   Thermal stability and mechanical properties of Mg-Y-Cu-M (M = Ag, Pd) bulk amorphous alloys [J].
Amiya, K ;
Inoue, A .
MATERIALS TRANSACTIONS JIM, 2000, 41 (11) :1460-1462
[2]   The effect of Mg-Ca-Sr alloy degradation products on human mesenchymal stem cells [J].
Berglund, Ida S. ;
Dirr, Elliott W. ;
Ramaswamy, Vidhya ;
Allen, Josephine B. ;
Allen, Kyle D. ;
Manuel, Michele V. .
JOURNAL OF BIOMEDICAL MATERIALS RESEARCH PART B-APPLIED BIOMATERIALS, 2018, 106 (02) :697-704
[3]   Effect of Mn addition on corrosion properties of biodegradable Mg-4Zn-0.5Ca-xMn alloys [J].
Cho, Dae Hyun ;
Lee, Byoung Woo ;
Park, Jin Young ;
Cho, Kyung Mox ;
Park, Ik Min .
JOURNAL OF ALLOYS AND COMPOUNDS, 2017, 695 :1166-1174
[4]   Topological instability, average electronegativity difference and glass forming ability of amorphous alloys [J].
de Oliveira, M. F. ;
Pereira, F. S. ;
Bolfarini, C. ;
Kiminami, C. S. ;
Botta, W. J. .
INTERMETALLICS, 2009, 17 (04) :183-185
[5]   Temporary scaffolding of coronary arteries with bioabsorbable magnesium stents:: a prospective, non-randomised multicentre trial [J].
Erbel, Raimund ;
Di Mario, Carlo ;
Bartunek, Jozef ;
Bonnier, Johann ;
de Bruyne, Bernard ;
Eberli, Franz R. ;
Erne, Paul ;
Haude, Michael ;
Heublein, Bernd ;
Horrigan, Mark ;
Ilsley, Charles ;
Boese, Dirk ;
Koolen, Jacques ;
Luescher, Thomas F. ;
Weissman, Neil ;
Waksman, Ron .
LANCET, 2007, 369 (9576) :1869-1875
[6]   Tribocorrosion behaviors of a biodegradable Mg65Zn30Ca5 bulk metallic glass for potential biomedical implant applications [J].
Hua, Nengbin ;
Chen, Wenzhe ;
Wang, Qianting ;
Guo, Qiaohang ;
Huang, Youting ;
Zhang, Tao .
JOURNAL OF ALLOYS AND COMPOUNDS, 2018, 745 :111-120
[7]   Relation between corrosion behavior and microstructure of Mg-Zn-Y alloys prepared by rapid solidification at various cooling rates [J].
Izumi, Shogo ;
Yamasaki, Michiaki ;
Kawamura, Yoshihito .
CORROSION SCIENCE, 2009, 51 (02) :395-402
[8]   Biodegradable Mg-Zn-Ca-Sr bulk metallic glasses with enhanced corrosion performance for biomedical applications [J].
Li, Haifei ;
Pang, Shujie ;
Liu, Ying ;
Sun, Lulu ;
Liaw, Peter K. ;
Zhang, Tao .
MATERIALS & DESIGN, 2015, 67 :9-19
[9]   Effect of trace HA on microstructure, mechanical properties and corrosion behavior of Mg-2Zn-0.5Sr alloy [J].
Li, Jian-Xing ;
Zhang, Yuan ;
Li, Jing-Yuan ;
Xie, Jian-Xin .
JOURNAL OF MATERIALS SCIENCE & TECHNOLOGY, 2018, 34 (02) :299-310
[10]   Bulk metallic glasses [J].
Löffler, JF .
INTERMETALLICS, 2003, 11 (06) :529-540
123