Effects of Cannabis Use on Human Behavior, Including Cognition, Motivation, and Psychosis: A Review

被引:595
作者
Volkow, Nora D. [1 ]
Swanson, James M. [2 ]
Evins, A. Eden [3 ,4 ]
DeLisi, Lynn E. [5 ]
Meier, Madeline H. [6 ]
Gonzalez, Raul [7 ]
Bloomfield, Michael A. P. [8 ,9 ]
Curran, H. Valerie [10 ]
Baler, Ruben [1 ]
机构
[1] NIDA, NIH, 6001 Execut Blvd, Bethesda, MD 20892 USA
[2] Univ Calif Irvine, Child Dev Ctr, Irvine, CA USA
[3] Massachusetts Gen Hosp, Dept Psychiat, Ctr Addict Med, Boston, MA 02114 USA
[4] Harvard Univ, Sch Med, Boston, MA USA
[5] Harvard Univ, Sch Med, Vet Affairs Boston Healthcare Syst, Boston, MA USA
[6] Arizona State Univ, Dept Psychol, Tempe, AZ 85287 USA
[7] Florida Int Univ, Dept Psychol, Ctr Children & Families, Miami, FL 33199 USA
[8] UCL, Div Psychiat, London, England
[9] Hammersmith Hosp, MRC, Ctr Clin Sci, Psychiat Imaging Grp, London, England
[10] UCL, Clin Psychopharmacol Unit, Clin Hlth Psychol, London, England
基金
英国医学研究理事会; 美国国家卫生研究院;
关键词
HIGH-POTENCY CANNABIS; GENETIC-VARIATION; ADULT PSYCHOSIS; RISK; SCHIZOPHRENIA; MEMORY; ASSOCIATION; ADOLESCENT; MARIJUANA; MODERATION;
D O I
10.1001/jamapsychiatry.2015.3278
中图分类号
R749 [精神病学];
学科分类号
100205 ;
摘要
With a political debate about the potential risks and benefits of cannabis use as a backdrop, the wave of legalization and liberalization initiatives continues to spread. Four states (Colorado, Washington, Oregon, and Alaska) and the District of Columbia have passed laws that legalized cannabis for recreational use by adults, and 23 others plus the District of Columbia now regulate cannabis use for medical purposes. These policy changes could trigger a broad range of unintended consequences, with profound and lasting implications for the health and social systems in our country. Cannabis use is emerging as one among many interacting factors that can affect brain development and mental function. To inform the political discourse with scientific evidence, the literature was reviewed to identify what is known and not known about the effects of cannabis use on human behavior, including cognition, motivation, and psychosis.
引用
收藏
页码:292 / 297
页数:6
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