Modeling the active sites of bacteriophage T7 lysozyme, bovine 5-aminolevulinate dehydratase, and peptide deformylase:: synthesis and structural characterization of a bis(pyrazolyl)(thioalkoxy)hydroborato zinc complex, [(Ph2CHS)BpBu-t,Pr-i]ZnI

被引：61
作者：
Ghosh, P [1 ]
Parkin, G [1 ]
机构：
[1] Columbia Univ, Dept Chem, New York, NY 10027 USA
来源：
CHEMICAL COMMUNICATIONS | 1998年 / 03期
关键词：
D O I：
10.1039/a707444a
中图分类号：
O6 [化学];
学科分类号：
0703 ;
摘要：
Insertion of thiobenzophenone into a B-H bond of [Bp(But,Pri)]ZnI achieves the synthesis of [(Ph2CHS)Bp(But,Pri)]ZnI, a complex in which the in situ generated [NNS] donor ligand models the binding of the histidine and cysteine residues at the active sites of bacteriophage T7 lysozyme, bovine 5-aminolevulinate dehydratase and peptide deformylase.
引用
收藏
页码：413 / 414
页数：2
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