Clinical efficacy of magnesium supplementation in patients with type 2 diabetes

被引：50
作者：
Yokota, K
Kato, M
Lister, F
Li, H
Hayakawa, T
Kikuta, T
Kageyama, S
Tajima, N
机构：
[1] Jikei Univ, Sch Med, Matier Co Ltd, Dept Internal Med, Tokyo 201, Japan
[2] Jikei Univ, Sch Med, Matier Co Ltd, Kato Med Ctr, Tokyo 201, Japan
[3] Jikei Univ, Sch Med, Matier Co Ltd, Dept Anat, Tokyo 201, Japan
[4] Jikei Univ, Sch Med, Matier Co Ltd, Dept Clin Pharmacol & Therapeut, Tokyo 201, Japan
来源：
JOURNAL OF THE AMERICAN COLLEGE OF NUTRITION | 2004年 / 23卷 / 05期
关键词：
magnesium supplementation; type 2 diabetes mellitus; hypertension; insulin-resistance; hypertriglyceridemia; life style-related diseases;
D O I：
10.1080/07315724.2004.10719390
中图分类号：
R15 [营养卫生、食品卫生]; TS201 [基础科学];
学科分类号：
100403 ;
摘要：
Effects of magnesium (Mg) supplementation on nine mild type 2 diabetic patients with stable glycemic control were investigated. Water from a salt lake with a high natural Mg content (7.1%) (MAG21) was used for supplementation after dilution with distilled water to 100mg/100mL; 300mL/day was given for 30 days. Fasting serum immunoreactive insulin level decreased significantly, as did HOMAsquareR (both p < 0.05). There was also a marked decrease of the mean triglyceride level after supplementation. The patients with hypertension showed significant reduction of systolic (p < 0.01), diastolic (p = 0.0038), and mean (p < 0.01) blood pressure. The salt lake water supplement, MAG21, exerted clinical benefit as a Mg supplement in patients with mild type 2 diabetes mellitus.
引用
收藏
页码：506S / 509S
页数：4
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