Efficacy of combined porcine reproductive and respiratory syndrome virus and Mycoplasma hyopneumoniae vaccination in piglets

被引：11

作者：

Drexler, C. S. ^{[1
]}

Witvliet, M. H. ^{[1
]}

Raes, M. ^{[1
]}

van de Laar, M. ^{[1
]}

Eggen, A. A. S. ^{[1
]}

Thacker, E. L. ^{[2
]}

机构：

[1] Intervet Schering Plough Anim Hlth, NL-5830 AA Boxmeer, Netherlands

[2] Iowa State Univ, Dept Vet Microbiol & Prevent Med, Ames, IA 50011 USA

来源：

VETERINARY RECORD | 2010年 / 166卷 / 03期

关键词：

ENZOOTIC PNEUMONIA; IMMUNE-RESPONSE; PIGS; CHALLENGE; INFECTION; POTENTIATION; PROTECTION; VACCINES; STRAINS; IMPACT;

D O I：

10.1136/vr.c176

中图分类号：

S85 [动物医学（兽医学）];

学科分类号：

0906 ;

摘要：

Three vaccination challenge studies were performed to evaluate the impact on vaccine efficacy of combining porcine reproductive and respiratory syndrome virus (PRRSV) and Mycoplasma hyopneumoniae vaccines. Piglets were vaccinated with either a M hyopneumoniae bacterin, a modified live PRRSV vaccine based on a European-type PRRSV strain, or a combination of both vaccines, followed by experimental infection with either M hyopneumoniae or PRRSV. Vaccine efficacy was evaluated by assessing lung lesion scores form hyopneumoniae and measuring viraemia for PRRSV. There were no significant differences between the protective efficacy of the combined vaccine protocol and the protective efficacy of the two single vaccines, indicating that PRRSV vaccination did not interfere with M hyopneumoniae vaccine efficacy and vice versa.

引用

页码：70 / 74

页数：5

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