Monoterpene glycosides, phenylpropanoids, and acacetin glycosides from Dracocephalum foetidum

被引:27
作者
Selenge, Erdenechimeg [1 ]
Murata, Toshihiro [1 ]
Tanaka, Shiho [1 ]
Sasaki, Kenroh [1 ]
Batkhuu, Javzan [2 ]
Yoshizaki, Fumihiko [1 ]
机构
[1] Tohoku Pharmaceut Univ, Dept Pharmacognosy, Aoba Ku, Sendai, Miyagi 9818558, Japan
[2] Natl Univ Mongolia, Sch Biol & Biotechnol, Ulaanbaata, Mongolia
关键词
Dracocephalum foetidum; Lamiaceae; Limonene glycoside; Phenylpropanoid; Hyaluronidase inhibitory activity; DPPH radical scavenging activity; HYALURONIDASE INHIBITORS; CHEMICAL-CONSTITUENTS; ESSENTIAL OIL; FLAVONOIDS; IDENTIFICATION; PLANTS; L; DERIVATIVES; PARTS;
D O I
10.1016/j.phytochem.2014.02.007
中图分类号
Q5 [生物化学]; Q7 [分子生物学];
学科分类号
071010 ; 081704 ;
摘要
Chemical investigation of the acetone extract from the aerial parts of the Mongolian medicinal plant Dracocephalum foetidum resulted in the isolation of three limonene glycosides, a caffeic acid trimer, four rosmarinic acid glucosides, and five acacetin acyl glycosides, together with 13 known natural products. The chemical structures of all of the compounds were determined by spectroscopic analyses. Among these compounds three showed hyaluronidase inhibitory activity. In addition, one other compound showed stronger 1,1-diphenyl-2-picrylhydrazyl radical scavenging activity than the positive control Trolox, whereas three other compounds demonstrated a similar activity to that of Trolox. (C) 2014 Elsevier Ltd. All rights reserved.
引用
收藏
页码:91 / 100
页数:10
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