Morphological and mechanical properties of tannic acid/PAAm semi-IPN hydrogels for cell adhesion

被引：32

作者：

Hu, Xinyu ^{[1
]}

Wang, Yongmei ^{[1
]}

Zhang, Liangliang ^{[1
]}

Xu, Man ^{[1
]}

机构：

[1] CAF, Inst Chem Ind Forestry Prod, Jiangsu Prov Biomass Energy & Mat Lab, Nanjing 210042, Jiangsu, Peoples R China

来源：

POLYMER TESTING | 2017年 / 61卷

关键词：

Tannic acid; Cryogels; Macropores; Cell adhesion; High elasticity; Degradation; GELATIN; METHACRYLATE); CHITOSAN; ACID; POLYACRYLAMIDE; SCAFFOLDS; NETWORKS; CRYOGELS; GRAPHENE; RELEASE;

D O I：

10.1016/j.polymertesting.2017.05.034

中图分类号：

TB3 [工程材料学];

学科分类号：

0805 ; 080502 ;

摘要：

A series of hydrogels were fabricated from tannic acid (TA), a typical plant polyphenol widely present in wood, and polyacrylamide (PAAm) by semi-IPN and cryogelation techniques. The introduction of TA into the PAAm network endows the system with enhanced cell adhesion properties. The cryogels with open interconnected macropores had a superfast swelling rate and a high swelling ratio, as well as high elasticity in response to compression. The degradation of the hydrogels can be tuned by modulating the content of cross-linker poly(ethylene glycol) diacrylate (PEGDA). Cytotoxicity results revealed that the hydrogels were non-toxic to COS-7 cells. All these results suggested that TA/PAAm semi-IPN hydrogels have great potential for applications in tissue engineering. (C) 2017 Elsevier Ltd. All rights reserved.

引用

页码：314 / 323

页数：10

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